ID   A0A2S4KW41_9HYPO        Unreviewed;       576 AA.
AC   A0A2S4KW41;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Polyamine aminopropyltransferase {ECO:0000313|EMBL:POR34404.1};
GN   ORFNames=TPAR_05364 {ECO:0000313|EMBL:POR34404.1};
OS   Tolypocladium paradoxum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Tolypocladium.
OX   NCBI_TaxID=94208 {ECO:0000313|EMBL:POR34404.1, ECO:0000313|Proteomes:UP000237481};
RN   [1] {ECO:0000313|EMBL:POR34404.1, ECO:0000313|Proteomes:UP000237481}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRBC 100945 {ECO:0000313|EMBL:POR34404.1,
RC   ECO:0000313|Proteomes:UP000237481};
RA   Quandt C.A., Patterson W., Spatafora J.W.;
RT   "Harnessing the power of phylogenomics to disentangle the directionality
RT   and signatures of interkingdom host jumping in the parasitic fungal genus
RT   Tolypocladium.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POR34404.1}.
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DR   EMBL; PKSG01000525; POR34404.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S4KW41; -.
DR   STRING; 94208.A0A2S4KW41; -.
DR   OrthoDB; 5489391at2759; -.
DR   Proteomes; UP000237481; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   NCBIfam; NF037959; MFS_SpdSyn; 1.
DR   Pfam; PF01564; Spermine_synth; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237481};
KW   Transferase {ECO:0000313|EMBL:POR34404.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        142..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        167..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   576 AA;  62481 MW;  20D2F9A91EBEA93D CRC64;
     MSAERTDEVP SEGFTPERFE RELKDLATKA KKDTWSSRAA GQLSVYAKAG FLLALLGVYS
     NVSQLALSPV YGSIPASTWH SKLLMTGCFL GWAGNAALRD FLPATAAQTI PLVALYAPAV
     QFLLCKYSGQ LGARWGPVAT EGLTLFPLAV LTAAAVADYL EGARLTMLPG FVAAAAPGLG
     SWGLFRFAEQ HAARHLQANM GSAIIYTRLC LELVLGALYA VFARSRFLVY ALPPLLHTLV
     INPHVASPAA TSALVSSMMS DGWLLIERRE SVTGYISVVQ SMQDGYRVMR CDHSLLGGEW
     IQARGQVVSE PIYGVFAMLE AVRLAERETP VTDEDAHALV VGLGVGTTPS ALVVHGINTT
     VVEIDPVVYE LAARYFDLKE NNPPVLEDAV GYTSALAAAA PETYDYIVHD VFTGGAEPVE
     LFTLEFLQGL GALLKPDGVI AINYAGDLAL PAPGIIYRTV KQVFPTCRIF REMPPDAEAI
     KEKGTDFTNM VIFCTRSAMP LTFRAPTTED YLQSSAREEF LHLSNEIPQA EFLSGGDATI
     LRKNDTSAVV KWHEQSAMGH WAVMRTALPA MVWEQW
//