ID A0A2S4L2S4_9HYPO Unreviewed; 588 AA.
AC A0A2S4L2S4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 22-FEB-2023, entry version 13.
DE RecName: Full=Pre-mRNA-processing protein 45 {ECO:0000256|ARBA:ARBA00022160, ECO:0000256|RuleBase:RU367140};
GN ORFNames=TPAR_03032 {ECO:0000313|EMBL:POR36732.1};
OS Tolypocladium paradoxum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Tolypocladium.
OX NCBI_TaxID=94208 {ECO:0000313|EMBL:POR36732.1, ECO:0000313|Proteomes:UP000237481};
RN [1] {ECO:0000313|EMBL:POR36732.1, ECO:0000313|Proteomes:UP000237481}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRBC 100945 {ECO:0000313|EMBL:POR36732.1,
RC ECO:0000313|Proteomes:UP000237481};
RA Quandt C.A., Patterson W., Spatafora J.W.;
RT "Harnessing the power of phylogenomics to disentangle the directionality
RT and signatures of interkingdom host jumping in the parasitic fungal genus
RT Tolypocladium.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in pre-mRNA splicing.
CC {ECO:0000256|RuleBase:RU367140}.
CC -!- SUBUNIT: Associated with the spliceosome.
CC {ECO:0000256|RuleBase:RU367140}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU367140}.
CC -!- SIMILARITY: Belongs to the SNW family. {ECO:0000256|ARBA:ARBA00010197,
CC ECO:0000256|RuleBase:RU367140}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POR36732.1}.
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DR EMBL; PKSG01000302; POR36732.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4L2S4; -.
DR STRING; 94208.A0A2S4L2S4; -.
DR OrthoDB; 5490078at2759; -.
DR Proteomes; UP000237481; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR InterPro; IPR017862; SKI-int_prot_SKIP.
DR InterPro; IPR004015; SKI-int_prot_SKIP_SNW-dom.
DR PANTHER; PTHR12096; NUCLEAR PROTEIN SKIP-RELATED; 1.
DR PANTHER; PTHR12096:SF0; SNW DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF02731; SKIP_SNW; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU367140};
KW mRNA splicing {ECO:0000256|RuleBase:RU367140};
KW Nucleus {ECO:0000256|RuleBase:RU367140};
KW Reference proteome {ECO:0000313|Proteomes:UP000237481};
KW Spliceosome {ECO:0000256|RuleBase:RU367140}.
FT DOMAIN 190..348
FT /note="SKI-interacting protein SKIP SNW"
FT /evidence="ECO:0000259|Pfam:PF02731"
FT REGION 1..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 588 AA; 66041 MW; 4621CF905D6676B6 CRC64;
MASIAASLQA SLPKPKYTGE DEEEASRSQQ RGPRIVGAGH LDETQVVLKR AGPPPYGQRS
GWRPRSQEDF GDGGAFPEIP VAQYPLDMGK KNATTSNALA IQVDAEGKVK YDAIARRGHG
DGRIVHTSFK DLIPLRQRAD AGEIDLSRPD RDSVAATTEK TKNALAALVS GAVAAQKPKN
VNVGNRRDPT FVRYTPANQM GDSSRKQDRI MKIVERQRDP MEPPKFKHKK IPRGPPSPPP
PVMHSPPRKL TAEDQEMWKI PPPVSNWKNP KGFTVPLDKR LAADGRGLQD IAINDKHAQF
AEAVKMAERH AREEVQQRAM MQQRLAEKEK AQKEDNLRAL AQKAREERAA AGRRDSRTSR
DSRESRDSRD SRDSRSRSRS YSYSESGSDS EDADVREREK ARQERRKEEE RKLRQTRMGT
ERRMQVMARE QNRDISEKVA LGLAKPTQSK ETMYDSRLFN QTSGFDSGFN EDNHYDKPLF
AAQDAISSIY RPRANMEDDD GEAADKEMAK IQKTSRFGEA LGKGTFKGAA EVEAREGPVQ
FEKETADPFN VDKFLSEVDQ NSSSKRGYGL QDEGSRQSKR PRVEDDDD
//
