ID   A0A2S4LAS8_9HYPO        Unreviewed;       574 AA.
AC   A0A2S4LAS8;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=TPAR_00290 {ECO:0000313|EMBL:POR39521.1};
OS   Tolypocladium paradoxum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Ophiocordycipitaceae; Tolypocladium.
OX   NCBI_TaxID=94208 {ECO:0000313|EMBL:POR39521.1, ECO:0000313|Proteomes:UP000237481};
RN   [1] {ECO:0000313|EMBL:POR39521.1, ECO:0000313|Proteomes:UP000237481}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRBC 100945 {ECO:0000313|EMBL:POR39521.1,
RC   ECO:0000313|Proteomes:UP000237481};
RA   Quandt C.A., Patterson W., Spatafora J.W.;
RT   "Harnessing the power of phylogenomics to disentangle the directionality
RT   and signatures of interkingdom host jumping in the parasitic fungal genus
RT   Tolypocladium.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POR39521.1}.
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DR   EMBL; PKSG01000034; POR39521.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S4LAS8; -.
DR   STRING; 94208.A0A2S4LAS8; -.
DR   OrthoDB; 3085104at2759; -.
DR   Proteomes; UP000237481; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237481};
KW   Signal {ECO:0000256|RuleBase:RU361235}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT   CHAIN           21..574
FT                   /note="Carboxylic ester hydrolase"
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT                   /id="PRO_5015375769"
FT   DOMAIN          40..519
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   574 AA;  63271 MW;  CAACA85C2F6B5062 CRC64;
     MVSVRFVMVA WLLSAGCATA NPTVVDTQHE VTYRGLHRNG IEVFLNIPYG QDTGGASRFK
     PPKPRVAARG STIHANAYGP ACPQQLGGWV VPISLSNVTK ISEDCLNLNV ARPKDTCVHD
     RLPVLVFLHG GSFWTGQNQE VTISPDGMIL QSVKNGLPVI HVAMNYRLGF FGFAQSDALK
     SEGSENAGLR DQRLALEWVR DNIGQFGGDP ERITIFGQSS GGLSVGMQIM AFGASKPVPF
     QQGICESQAL EPGITGNFTI DAMRALVEYV GCNSSSLHSK DTVACLRMFD METLLNASLT
     TYHSDIVHNI GDIWLPAVDG DFLPSAPSQL IRQGRFANVT TMIGWCEDDV TFFTDPNIKT
     PSDTLNFISA YAPDMTQDSL HKLLSLYPAS DFPAGKSLSS EFYRSARIFR DILMTCQPMW
     YAKHIAAAGN DVYLYDWNQT ILDPILAYTM NQTGFGPIHT SEFAYIFGNL SHYDTNGYPF
     HPSKSDYKLR DRGSRSWSTF ASIGKPSLEG HDTFQGFTPG FRTVNETHVF VIGASHEGLS
     ALDGPHAYPE IANQKLRERC DFINSPMIIE QLRY
//