ID A0A2S4MZ27_SHIFL Unreviewed; 353 AA.
AC A0A2S4MZ27; Q7C0I2; Q83QL7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Permease {ECO:0000313|EMBL:AAN44038.1};
GN Name=perM {ECO:0000313|EMBL:AAN44038.1};
GN OrderedLocusNames=SF2537 {ECO:0000313|EMBL:AAN44038.1};
OS Shigella flexneri.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623 {ECO:0000313|EMBL:AAN44038.1, ECO:0000313|Proteomes:UP000001006};
RN [1] {ECO:0000313|EMBL:AAN44038.1, ECO:0000313|Proteomes:UP000001006}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a {ECO:0000313|Proteomes:UP000001006};
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC family. {ECO:0000256|ARBA:ARBA00009773}.
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DR EMBL; AE005674; AAN44038.1; -; Genomic_DNA.
DR RefSeq; NP_708331.1; NC_004337.2.
DR RefSeq; WP_000892049.1; NZ_WPGW01000011.1.
DR AlphaFoldDB; A0A2S4MZ27; -.
DR PaxDb; 198214-SF2537; -.
DR GeneID; 1025318; -.
DR KEGG; sfl:SF2537; -.
DR PATRIC; fig|198214.7.peg.3033; -.
DR OMA; WVLMRVI; -.
DR Proteomes; UP000001006; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR002549; AI-2E-like.
DR PANTHER; PTHR21716:SF77; PERMEASE PERM-RELATED; 1.
DR PANTHER; PTHR21716; TRANSMEMBRANE PROTEIN; 1.
DR Pfam; PF01594; AI-2E_transport; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001006};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 353 AA; 39222 MW; 176EEE72EE7238ED CRC64;
MLEMLMQWYR RRFSDPEAIA LLVILVAGFG IIFFFSGLLA PLLVAIVLAY LLEWPTVRLQ
SIGCSRRWAT SIVLVVFVGI LLLMAFVVLP IAWQQGIYLI RDMPGMLNKL SDFAATLPRR
YPVLMDAGII DAMAENMRSR MLTMGDSVVK ISLASLVGLL TIAVYLVLVP LMVFFLLKDK
EQMLNAVRRV LPRNRGLAGQ VWKEMNQQIT NYIRGKVLEM IVVGIATWLG FLLFGLNYSL
LLAVLVGFSV LIPYIGAFVV TIPVVGVALF QFGAGTEFWS CFAVYLIIQA LDGNLLVPVL
FSEAVNLHPL VIILSVVIFG GLWGFWGVFF AIPLATLIKA VIHAWPDGQI AQE
//
