ID A0A2S4NAK8_9FLAO Unreviewed; 943 AA.
AC A0A2S4NAK8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=Q361_10225 {ECO:0000313|EMBL:POS02715.1};
OS Flavobacterium croceum DSM 17960.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1121886 {ECO:0000313|EMBL:POS02715.1, ECO:0000313|Proteomes:UP000237056};
RN [1] {ECO:0000313|EMBL:POS02715.1, ECO:0000313|Proteomes:UP000237056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17960 {ECO:0000313|EMBL:POS02715.1,
RC ECO:0000313|Proteomes:UP000237056};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase I: the one thousand microbial
RT genomes (KMG-I) project.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POS02715.1}.
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DR EMBL; PQNY01000002; POS02715.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4NAK8; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000237056; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000237056};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 608..939
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 943 AA; 105556 MW; EBDCF7CE7A7C66BB CRC64;
MPSFEEHIEI IGARAHNLKN IDVTIPRDKL VVITGLSGSG KSSLAFDTIY AEGQRRYIET
FSAYARQFLG GLERPDVDKI DGLSPVIAIE QKTTSKSPRS TVGTITEIYD FLRLLFARAA
DAYSYNTGEK MVSYSDEQIK DLIIESFQGK RINILAPVIR ARKGHYAELF QHIAKQGFVK
VRVNGEIVDI TPGMKLDRYK THDIEIVIDR IEIDNATDTQ KRLSESINTA MYHGDDVMMV
LEQNQKEVRF FSRTLMCPTT GISYQNPEPN LFSFNSPKGA CDHCNGLGTV NEINTQKIIP
NTKISIKQGA IVPLGEYKSS WMFKQLEIIG EKFGFSLTDS FEKIPQEAVD MILNGGHEKF
SVKSKTAGVT KEYKIEFEGI SNFIKSQFND SESTSLKRWA NDFMDEVKCP VCNGSRLKKE
SLYFKINEKN IAELSAMDLS ELTAWFENLN ELLSEKQKAI ASEIVKEIND RLRFLMNVGL
NYLSLQRSSK SLSGGEAQRI RLATQIGSQL VGVLYILDEP SIGLHQRDNE RLIKSLENLR
DIGNSVLVVE HDKDMIERAD WVIDIGPKAG RHGGKIISEG TPKSLLAEHT LTAQYLNGEK
SIEIPKERRK GNGKKLKLKG ATGNNLKNVS VEFPLGTLIC VTGVSGSGKS TLINETLYPI
LNEHFFNAVK KPMPYQKIEG LEHIDKVIDI DQSPIGRTPR SNPATYTDVF SDIRNLFTQT
PEAMIRGYKA GRFSFNVKGG RCETCEGSGV RTIEMAFLPD VYVECETCQG KRFNRETLEI
RYKGKSISDV LNMTVDEAVD FFENIPKIYR KVKTIQDVGL GYITLGQQST TLSGGEAQRV
KLATELSKKD TGNTFYIMDE PTTGLHFEDI RVLMEVIQKL VNKGNTVLII EHNLDVIKLA
DYIIDVGPEG GKGGGQIIAT GTPEQVSKNK ESHTARFLKM ELQ
//
