ID A0A2S4PM57_9PEZI Unreviewed; 371 AA.
AC A0A2S4PM57;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=EPUL_006049 {ECO:0000313|EMBL:POS83126.1};
OS Erysiphe pulchra.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=225359 {ECO:0000313|EMBL:POS83126.1, ECO:0000313|Proteomes:UP000237438};
RN [1] {ECO:0000313|EMBL:POS83126.1, ECO:0000313|Proteomes:UP000237438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cflorida {ECO:0000313|EMBL:POS83126.1};
RA Wadl P.A., Mack B.M., Moore G., Beltz S.B.;
RT "Development of genomic resources for the powdery mildew, Erysiphe
RT pulchra.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POS83126.1}.
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DR EMBL; PEDP01001873; POS83126.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4PM57; -.
DR STRING; 225359.A0A2S4PM57; -.
DR OrthoDB; 1133at2759; -.
DR Proteomes; UP000237438; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000237438}.
FT DOMAIN 16..288
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 371 AA; 41308 MW; 6AF78772872BD50A CRC64;
MSDLSEKKDF DLGNVLVIGG CGFLGHHIVD VLHKSYKCVI AVLDLHTTRN RRTDIDGIQY
FNGDITSMES ILPIFLKLEP SIVIHTASPT LTGGSNELYK KVNVDGTRCV IEACQKVNVK
ALVYTSSASI ISDNVSDLIN ADERWPVVPS KYQTELISVT AQAESLVLAS NRSSSYPSLL
TCSLRPAGIF GEGDVQLIPN MLKVYENSKT GFQLGDNSNL FDFTYVGNVA QAHCLAAAAL
RATSQLSTTP LSHEKVDGEA FFITNDQPIY FWDFARAVWK AAGSDKGTEH VWEISQSMGM
LIGGIMEYVL WLMGKVPSLT RRQVRYSCMT RYYDCGKAKR LLGYKPEVHL WEGIQRSVAW
FKNKNKQRKI E
//
