ID A0A2S4PV96_9PEZI Unreviewed; 539 AA.
AC A0A2S4PV96;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=L-ornithine N(5)-monooxygenase {ECO:0000256|ARBA:ARBA00018612};
DE EC=1.14.13.196 {ECO:0000256|ARBA:ARBA00012881};
DE AltName: Full=L-ornithine N(5)-oxygenase {ECO:0000256|ARBA:ARBA00030351};
DE Flags: Fragment;
GN ORFNames=EPUL_002723 {ECO:0000313|EMBL:POS85971.1};
OS Erysiphe pulchra.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=225359 {ECO:0000313|EMBL:POS85971.1, ECO:0000313|Proteomes:UP000237438};
RN [1] {ECO:0000313|EMBL:POS85971.1, ECO:0000313|Proteomes:UP000237438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cflorida {ECO:0000313|EMBL:POS85971.1};
RA Wadl P.A., Mack B.M., Moore G., Beltz S.B.;
RT "Development of genomic resources for the powdery mildew, Erysiphe
RT pulchra.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-ornithine + NADH + O2 = H2O + N(5)-hydroxy-L-ornithine +
CC NAD(+); Xref=Rhea:RHEA:41512, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:46911, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC ChEBI:CHEBI:78275; EC=1.14.13.196;
CC Evidence={ECO:0000256|ARBA:ARBA00001398};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-ornithine + NADPH + O2 = H2O + N(5)-hydroxy-L-ornithine +
CC NADP(+); Xref=Rhea:RHEA:41508, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:46911, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:78275; EC=1.14.13.196;
CC Evidence={ECO:0000256|ARBA:ARBA00001847};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- PATHWAY: Siderophore biosynthesis. {ECO:0000256|ARBA:ARBA00004924}.
CC -!- SIMILARITY: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-
CC oxygenase family. {ECO:0000256|ARBA:ARBA00007588}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POS85971.1}.
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DR EMBL; PEDP01000442; POS85971.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4PV96; -.
DR STRING; 225359.A0A2S4PV96; -.
DR OrthoDB; 5491437at2759; -.
DR Proteomes; UP000237438; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR025700; Lys/Orn_oxygenase.
DR PANTHER; PTHR38663; -; 1.
DR PANTHER; PTHR38663:SF1; ZGC:113276; 1.
DR Pfam; PF13434; Lys_Orn_oxgnase; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000237438}.
FT NON_TER 539
FT /evidence="ECO:0000313|EMBL:POS85971.1"
SQ SEQUENCE 539 AA; 60618 MW; 0E5380D0BEA6B92F CRC64;
MEVPVHDVLI IGSGPCGLAV ASRLKEQTPG SLFSDTEHQR FHFMRASAQS RLTSKPIRLS
RRSNIPAERL LSGPAIPNND LDMVVLDADG DQWMHSWNEN FKKLQISHLR SPMFFHPDPS
DRDGLRAFAY VKGRMNELKE IEGVVGKELS KHHRKQKQKK SSQKNITYLD ERFRDDYFRP
SQALFKEYCE DIARRYGILN IVQKSRVDSI SFDSDEEIFT LQTSTGEKKS RIIVLAIGSA
LDPSLPPDCP FCNPHNVSHI MSAKVNSNLL TNQDVKYRTK SVLIVGGGLT SAQVAKVLAD
EGISRIFLIL RGKLKTKHFD VDLHWLAKYK NRSMSEFYFA DSDHERWEMM KSARGGGSVN
PEFRTVIEKL QKRGILVLKE DTVIKNASWQ STSASWSVDL QTDEQKTENL LVNYVIYATG
TPVNISSLPI IQPIMKQYPI DTVGGMPCLT AELMWKEEVP LFATGKLGGL RLGPAAGNLE
GARIGAEFIA GKIAELLPRW KDFESPLIDS SEKNSNEITV DLRRLGLGQA NQFEILSQT
//
