ID A0A2S4PWM6_9PEZI Unreviewed; 626 AA.
AC A0A2S4PWM6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=EPUL_002645 {ECO:0000313|EMBL:POS86435.1};
OS Erysiphe pulchra.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Erysiphales; Erysiphaceae; Erysiphe.
OX NCBI_TaxID=225359 {ECO:0000313|EMBL:POS86435.1, ECO:0000313|Proteomes:UP000237438};
RN [1] {ECO:0000313|EMBL:POS86435.1, ECO:0000313|Proteomes:UP000237438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Cflorida {ECO:0000313|EMBL:POS86435.1};
RA Wadl P.A., Mack B.M., Moore G., Beltz S.B.;
RT "Development of genomic resources for the powdery mildew, Erysiphe
RT pulchra.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POS86435.1}.
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DR EMBL; PEDP01000331; POS86435.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4PWM6; -.
DR STRING; 225359.A0A2S4PWM6; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000237438; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000237438}.
FT DOMAIN 89..209
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 626 AA; 69976 MW; DA7FD3F64E647670 CRC64;
MWNDEDNNPY GTAFDQSEST AYSIQHGFDG PRSPSTDDDS HGSGLRNRTE INTGYSDSEN
EEEEEEQKNK LLVPKKRGGY DSRIEQILYE NPDLPILIVD AGKSLETGSK YIVYTIRTGD
LEVRRRYSEF ASLRDAISRL HPTLVVPPIP EKHTMADYAA NPTQARQDQQ IIDLRKRMLA
VFLNRCRLMD DIRNDGVWWR FLDPNSSWNE VIHTHPVSSI PKSIMKAPPL DPANPTSAHA
FLPIPTSSAR LKAATNVSVN PQGMPNPSPE NCSNTANKTR GPRLTGRFPV NSSQLSESEL
DPYFINFESS SKDLELLLTG PLEKVNRRTL NHLSSLSLDF AELGARFNGF ALSETSSSLA
SAIERFGQAI DTSYLATEEL SSSLGASFAE PMRESALFAG VVRGLLRYRV LKRVQQEMIN
DELAKKRALL DSLEKSEIEA KRIEKYLHNT GSSNSPRTSV ASSNDQLKRE SQNQLAETAS
IDSDFPPTHG ETPPPSAAQG APSIDQQPPS HRKSSSGNFI TNKIFVRISH AVHGVVDVDP
ERTRRDLIGK TKEGISQLEQ AQKVAEQDVK DASFGILKDL NRFQAEKEDD LKRYMVSYAK
SQIDWAKKNL ETWEEAKTEI NKIDEN
//
