ID   A0A2S4V3D5_9BASI        Unreviewed;       738 AA.
AC   A0A2S4V3D5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Mechanosensitive ion channel MscS domain-containing protein {ECO:0000259|Pfam:PF00924};
GN   ORFNames=PSTT_10700 {ECO:0000313|EMBL:POW04018.1};
OS   Puccinia striiformis.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC   Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX   NCBI_TaxID=27350 {ECO:0000313|EMBL:POW04018.1, ECO:0000313|Proteomes:UP000239156};
RN   [1] {ECO:0000313|EMBL:POW04018.1, ECO:0000313|Proteomes:UP000239156}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=93-210 {ECO:0000313|EMBL:POW04018.1,
RC   ECO:0000313|Proteomes:UP000239156};
RA   Xia C.;
RT   "Gene loss provides genomic basis for host adaptation in cereal stripe rust
RT   fungi.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POW04018.1}.
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DR   EMBL; PKSL01000117; POW04018.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S4V3D5; -.
DR   VEuPathDB; FungiDB:PSHT_06915; -.
DR   VEuPathDB; FungiDB:PSTT_10700; -.
DR   Proteomes; UP000239156; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR023408; MscS_beta-dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   PANTHER; PTHR31323; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR   PANTHER; PTHR31323:SF1; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239156};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        103..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        140..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          494..560
FT                   /note="Mechanosensitive ion channel MscS"
FT                   /evidence="ECO:0000259|Pfam:PF00924"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          682..738
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        684..711
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   738 AA;  82569 MW;  9598564DC065956E CRC64;
     MCSLPYKNSG QDPCPRSIPL SPSSSASTPT LPYQQAEKEF DHLHPPRSEF DHPKSTFLNM
     SSFRNQTGHQ RSFSVGIPGQ DQGEGRQGHA VLKPPRGFLQ GHILLRWFFF ITPILMIVWI
     PGFIAFALPD KHLKVAGVEL LWWSAWLSVA WLGWWVGLIV GALTPLLFKH VIGIACSPDF
     VVKWYSFLKP MRNVIMGAVW GVSTYISFSL LITRMSSGAS ESAAKALHLM SQALFGILLA
     SLTLVGEKIL IQAIASYFHQ RSYEDRISEQ KSAIQFITTL YRYTHDIGRA DTLDRALGAP
     TSAPEHTAKL FKCALKGVKN VARNTTSIFG TVASEIAGEQ ILQPNSPSSM VLSALSSANK
     SRHLARRIYY SFVPVTYRQV MVLGDILPCF QGDEESAQDS FAVFDKDRNG DCSLQEIELT
     CLELHRERLA LVAVSPQQLK LPPIRHLELI VCTTSEYTVS LLITVALLDI SFQTLLASAG
     TLVLGLSWLI GSTAQEILSS IIFLFVKHPY DVSDRVDVDD VSYVVKEMHL LYTVFRQTDG
     KISQIPHSSL NSKRVVNIRR SGPISEKFSW DVNFNTSFEK IEQLRGKMLE FLKAERRDYT
     PAFDVSIQDF EGQAQLTLQA DIKYKSNWQN GALKSQRRNK WVCALKQIMA EVEIYGPADA
     GHPSPKSEPT LIQLIDSPPL VLQQRGESPR SQQAQQKQPS EKSSGIQSVE LENRENVMRD
     DDDEEPGLPL NYIPLSPF
//