ID A0A2S4VZZ6_9BASI Unreviewed; 926 AA.
AC A0A2S4VZZ6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=PSTT_02583 {ECO:0000313|EMBL:POW15007.1};
OS Puccinia striiformis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=27350 {ECO:0000313|EMBL:POW15007.1, ECO:0000313|Proteomes:UP000239156};
RN [1] {ECO:0000313|EMBL:POW15007.1, ECO:0000313|Proteomes:UP000239156}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=93-210 {ECO:0000313|EMBL:POW15007.1,
RC ECO:0000313|Proteomes:UP000239156};
RA Xia C.;
RT "Gene loss provides genomic basis for host adaptation in cereal stripe rust
RT fungi.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POW15007.1}.
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DR EMBL; PKSL01000015; POW15007.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4VZZ6; -.
DR VEuPathDB; FungiDB:PSTT_02583; -.
DR Proteomes; UP000239156; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR PANTHER; PTHR12673:SF159; RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR JJ; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000239156}.
FT DOMAIN 25..245
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 505..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 725..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 816..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 67..119
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 510..536
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..755
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..799
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..901
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 902..926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 102728 MW; 72F75239347B5371 CRC64;
MKEYQLGQQG SRSAPDLVVD GILQRRLRAL IEIIETEDGY LKDLKRLDNF YLNRIINESS
TLKTKDKQII RRNIAQLIEL AERFNRRISI AIGKNYNELL RLEEDEAELD RIIERLAKAF
ISESPIFTIY EEYCARHTEA ADLIRAFQAT TEWNSLTSPN DFTTTTTLVE SSSSGPSEPS
RLNFSDYIIK PIQRIMRYPM LLNGLLNQLT STNQVQLPST RSRAIERVQQ ALWAMKQVAE
GVDQAKSLRE IELKTELIAS RMELHSSYRA AFVCLLGQIK LVGSLHILYH GPNLDQSEAF
KIKYHGIFLY QTHLVIVKVK RATVYEPRHW FPIRYFDLID ISDNSSLMPY SFSLKYRQHT
FEFGATCEPE KRCWINKLRD LKAEIDQLRS IQIMSAIPLS DDSIVSSINL TENVTTTPTT
TTTTNTTTTM MTTVVEGTSP SPIEPQPQEE QLVMDTMPTR VSQRLSRNVN TLLGRTAEVA
QAAIDLKLTE IFSEVLIMAR SHDNHSHHQL GTGGESSRTR TLSATGTISG KRNSNYHQVH
TFSRKRMSCL EPSTIGRLKE LPPPPIPDQD LNTTSIDSSN SSSTPTTAST SSLRRARSGP
ALVSNRSQSS LNRSEGTAAD ESPTLPIIHP SSRQSNTAIV IPVIETNHNS PILEEEHEVR
FSPDLCVRCI SPDQKLELHP PPPSSSLSKP IENHHQQQTS SGSSSNNSSS STLWLPGLKM
VRKLSRVGSR PSPSTISTTT STTSASNSTG VNGNKKVNAR MDRQASAPST SSRPSTSPHP
HQPSSSTTAT TTTTITTNEG YGNTFKRVFM KRNRSCVSTP STTDHPHLLS STSESHPLIS
CEEKENKSHL KNGVSEAIIK SSSSPSTSSS SPSPNPPPSS TGTTPPIPEG ETKPPPQPHP
TRSISITNTI RRARTTTARS SSSFFC
//
