ID   A0A2S4XTK8_9ACTN        Unreviewed;       394 AA.
AC   A0A2S4XTK8;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=THIF-type NAD/FAD binding fold domain-containing protein {ECO:0000259|Pfam:PF00899};
GN   ORFNames=C3486_15710 {ECO:0000313|EMBL:POX39959.1};
OS   Streptomyces sp. Ru73.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2080748 {ECO:0000313|EMBL:POX39959.1, ECO:0000313|Proteomes:UP000236956};
RN   [1] {ECO:0000313|EMBL:POX39959.1, ECO:0000313|Proteomes:UP000236956}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ru73 {ECO:0000313|EMBL:POX39959.1,
RC   ECO:0000313|Proteomes:UP000236956};
RA   Suneja G., Sharma R.;
RT   "Genome sequencing of cellulose degrading bacteria.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POX39959.1}.
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DR   EMBL; PQSQ01000030; POX39959.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S4XTK8; -.
DR   OrthoDB; 4426339at2; -.
DR   Proteomes; UP000236956; Unassembled WGS sequence.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR022291; Bacteriocin_synth_cyclodeHase.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   NCBIfam; TIGR03882; cyclo_dehyd_2; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000236956}.
FT   DOMAIN          126..370
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   394 AA;  41164 MW;  720DE5E2524C3148 CRC64;
     MLKPALRRGW RDRATVRFGV APAHAVVVGP VDGATGSLLD LIDGTRSIEE LEREAKALQL
     PPGHARELVG RLDAAGLLDS PAPGAPAAEA LQADLPAFDR LRPDLAALSV CHRDGTGADE
     RLWARRSARV RVRGTGRVGA SIAALLSAAG VGQVEVLDGG RVEPWDVLPA GFSPDRVGER
     RDVSARRLVN EYSPWARRPH ASLRSAHGAS LGSAPCASLD GPPPGDPPLA LTVLAPRDGL
     AAYAPDPRLA ESLVATGMPH LYVGVIEATG VVGPLVLPGD TACAGCWELR RTDVEPAWLR
     LLAQWRSGRA SPVVPACDAA LATTVAGLAA TQVLTYLDGY LPPCTGARTE LALPCMSWNI
     DQIEAHPECA CGAARSPATA AASDPRPRHA TMTE
//