ID   A0A2S4YM81_9ACTN        Unreviewed;       420 AA.
AC   A0A2S4YM81;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Alpha-1-antitrypsin {ECO:0000313|EMBL:POX49763.1};
GN   ORFNames=C3489_23875 {ECO:0000313|EMBL:POX49763.1};
OS   Streptomyces sp. Ru71.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2080746 {ECO:0000313|EMBL:POX49763.1, ECO:0000313|Proteomes:UP000237414};
RN   [1] {ECO:0000313|EMBL:POX49763.1, ECO:0000313|Proteomes:UP000237414}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ru71 {ECO:0000313|EMBL:POX49763.1,
RC   ECO:0000313|Proteomes:UP000237414};
RA   Suneja G., Sharma R.;
RT   "Genome sequencing of cellulose degrading bacteria.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:POX49763.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PQSS01000044; POX49763.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S4YM81; -.
DR   OrthoDB; 4318225at2; -.
DR   Proteomes; UP000237414; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF166; OS11G0650500 PROTEIN; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237414};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           31..420
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015609158"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          39..228
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   420 AA;  44120 MW;  F9221C7C4EBCFF99 CRC64;
     MIRRQRLAAG LGALLAALAA GLAFPAGAVA DETTASAPKV DLVIDVSGSM RTRDIDGQTR
     MSAAKQAFNE VLDATPEEVQ LGIRTLGATY PGDDRQTGCK DTAQLYKVGP LDRTEAKTAV
     ATLSPTGWTP IGPALLKAAG DLDGGTGSKR IVLISDGEDT CAPLDPCEVA REIAAKGIGL
     TIDTLGLVPN VKMRQQLSCI AEATGGTYTS VEHTDDLADK VNQLVDRAAD PVVTPVATDG
     AASCAKAPTL NSGLYTDREE FGQQRWYRVD VKPGQELRAS VSVAADRSMH PDYGVLLRAV
     TVHGREIVRG EAAGNGRTDV ISTGVRYPKA DSDDENAPAE TVCLAVTNSF SAAPGVKTTP
     GMPLELTVDV VDGPSQADDV ASFGLGRGWW LLGLLVLIGF LAGVVWGWLS RWRVAVWRTN
//