ID A0A2S4YT43_9ACTN Unreviewed; 338 AA.
AC A0A2S4YT43;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE SubName: Full=Type III polyketide synthase {ECO:0000313|EMBL:POX52042.1};
GN ORFNames=C3489_18825 {ECO:0000313|EMBL:POX52042.1};
OS Streptomyces sp. Ru71.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2080746 {ECO:0000313|EMBL:POX52042.1, ECO:0000313|Proteomes:UP000237414};
RN [1] {ECO:0000313|EMBL:POX52042.1, ECO:0000313|Proteomes:UP000237414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ru71 {ECO:0000313|EMBL:POX52042.1,
RC ECO:0000313|Proteomes:UP000237414};
RA Suneja G., Sharma R.;
RT "Genome sequencing of cellulose degrading bacteria.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POX52042.1}.
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DR EMBL; PQSS01000029; POX52042.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4YT43; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000237414; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877:SF99; 1,3,6,8-TETRAHYDROXYNAPHTHALENE SYNTHASE; 1.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000237414}.
FT DOMAIN 42..180
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 190..324
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 121
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 338 AA; 36877 MW; 8A80D6227993EC97 CRC64;
MEETLEFAQQ AHAGKPQLPL ALRLIRNTGV QKRHIVQPIE QTLRHPGFEE RNRIYEVESK
KRTPEVIEQA LANAELTARD IDAIIYVSCT GFLMPSLTAW LINKLGFRSD TRQIPIAQLG
CAAGGAAINR AHDFCMAHPG SNVLIVSCEL CSLCYQPTAD DIGSLLSDGL FGDAVAAAVV
RGNGGTGIEL ERNASYLIPD TEEWISYAVK DTGFHFQLDR RVPGTMEPLA PVLRELAKDH
SWDAGKLDFY IIHAGGPRIL DDLAKFLEVD RDVFRHSWST LTEYGNIASA VVLEAARRLM
EEETPQPGAT GLIAGFGPGI TAEMALGTWA DGSAQPVD
//
