ID A0A2S4Z2D8_9ACTN Unreviewed; 380 AA.
AC A0A2S4Z2D8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Class E sortase {ECO:0000313|EMBL:POX54963.1};
GN ORFNames=C3488_00805 {ECO:0000313|EMBL:POX54963.1};
OS Streptomyces sp. Ru72.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2080747 {ECO:0000313|EMBL:POX54963.1, ECO:0000313|Proteomes:UP000237426};
RN [1] {ECO:0000313|EMBL:POX54963.1, ECO:0000313|Proteomes:UP000237426}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ru72 {ECO:0000313|EMBL:POX54963.1,
RC ECO:0000313|Proteomes:UP000237426};
RA Suneja G., Sharma R.;
RT "Genome sequencing of cellulose degrading bacteria.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POX54963.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PQSR01000001; POX54963.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S4Z2D8; -.
DR OrthoDB; 5242879at2; -.
DR Proteomes; UP000237426; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd05830; Sortase_E; 1.
DR Gene3D; 2.40.260.10; Sortase; 1.
DR InterPro; IPR005754; Sortase.
DR InterPro; IPR023365; Sortase_dom-sf.
DR InterPro; IPR042003; Sortase_E.
DR NCBIfam; NF033747; class_E_sortase; 1.
DR NCBIfam; TIGR01076; sortase_fam; 1.
DR Pfam; PF04203; Sortase; 1.
DR SUPFAM; SSF63817; Sortase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000237426};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 167..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 279
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT ACT_SITE 348
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ SEQUENCE 380 AA; 41084 MW; 1AAF804BBE18B9D2 CRC64;
MTALRPERET GATYGDAAEQ GSSYGQQPYG DFGVWQGQDP GPQWQGAGEY GQQTPQQTYE
PQQGYDATAV LPSYDEPLPV DNETVALRAL DIEEARRAAN RPAEAAPAPG GRAARRKAAR
RHGRRGSGPQ TPEKAAGTPA QAPRSRVEAR RAARAQKPGA AVVASRVVGE LFITTGVVML
LFVTYQLWWS NVRAHQEAGS AAQHLQQDWA SGKREPGVFA PGQGFAILHI PKLDVVAPIA
EGTSKTEVLD KGMVGHYGEG SLKTAMPSDK TGNFGLAGHR NTHGEPFRYI NRLQPGDAIV
VETQDEYYVY KMTSMLPVTS PANTSVLDPI PKGSGFTAPG RYITLTTCTP EFTSKYRLIV
WGKMVEERPR SKGKPDALIS
//
