ID A0A2S5ACU8_9FLAO Unreviewed; 644 AA.
AC A0A2S5ACU8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:POY40401.1};
GN Name=mrdA {ECO:0000313|EMBL:POY40401.1};
GN ORFNames=C3L50_07090 {ECO:0000313|EMBL:POY40401.1};
OS Flavobacterium alvei.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=2080416 {ECO:0000313|EMBL:POY40401.1, ECO:0000313|Proteomes:UP000237310};
RN [1] {ECO:0000313|EMBL:POY40401.1, ECO:0000313|Proteomes:UP000237310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HR-AY {ECO:0000313|EMBL:POY40401.1,
RC ECO:0000313|Proteomes:UP000237310};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POY40401.1}.
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DR EMBL; PQVG01000003; POY40401.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S5ACU8; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000237310; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000237310}.
FT DOMAIN 46..209
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 247..577
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 644 AA; 72433 MW; 1D565BDD84EF5EE8 CRC64;
MRKVLLPSMI IIAASLLVLR LFYLQVINDS FKLKSDNNAI KIQYDYPERG YIYDRNGKLL
VANQPSYDIM VIPRDIKNLD TLEFCQLLAI SKEDFLEKIA KAKVYSPRLP SVFLAQLNKS
EFAAFQEKIR KFEGFYFQKR SLRDYQVNFG ANIFGFITQV SENLIAKNPY YNSGDLIGKQ
GVEESYEEVL RGIKGVKYIQ KDKYNREIGS FKEGKYDTIA VQGEDINLTI DMELQKYGEE
LMINKRGGIV AIEPKTGEIL ALVTAPNYDP AILVGRQRSK NYTMLYRDSI ANPLFDRGLL
AQYPPGSPFK ILTGLVGLQE NVIDTHSTFM CNHGFAYAPG RFQRCHCGGG SRDLNVGIYK
SCNAYFSNVY LRTIGKYKST PYAVDVWSNH VKSFGLGQFM GYDLPTGKKG KIPNSKTYKR
IYPGWGYSGK TIISNAIGQG EVLLTPIQLA NMMSAVANEG YYYTPHIIKK IEGEKIDKKF
TTKHVTTIDK SHFKPMIQGL FDVYNFGTAA GLRVEGIDIC GKTGTAENFA KINGKRTQLE
DHSIFVAFAP KDNPKIAIAI LVENGGFGSV IAGPIASLMI EKYLKGKITR TDLEKRTLER
SLQDQYAKLG GLSEVVKKEM RKKDSILKSK IVVPKVKIDT TKKP
//
