ID A0A2S5BIK3_9BASI Unreviewed; 1182 AA.
AC A0A2S5BIK3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Cyclin-dependent protein kinase inhibitor {ECO:0008006|Google:ProtNLM};
GN ORFNames=BMF94_0198 {ECO:0000313|EMBL:POY76608.1};
OS Rhodotorula taiwanensis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Microbotryomycetes; Sporidiobolales; Sporidiobolaceae; Rhodotorula.
OX NCBI_TaxID=741276 {ECO:0000313|EMBL:POY76608.1, ECO:0000313|Proteomes:UP000237144};
RN [1] {ECO:0000313|EMBL:POY76608.1, ECO:0000313|Proteomes:UP000237144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD1149 {ECO:0000313|EMBL:POY76608.1,
RC ECO:0000313|Proteomes:UP000237144};
RX PubMed=29375494;
RA Tkavc R., Matrosova V.Y., Grichenko O.E., Gostincar C., Volpe R.P.,
RA Klimenkova P., Gaidamakova E.K., Zhou C.E., Stewart B.J., Lyman M.G.,
RA Malfatti S.A., Rubinfeld B., Courtot M., Singh J., Dalgard C.L.,
RA Hamilton T., Frey K.G., Gunde-Cimerman N., Dugan L., Daly M.J.;
RT "Prospects for Fungal Bioremediation of Acidic Radioactive Waste Sites:
RT Characterization and Genome Sequence of Rhodotorula taiwanensis MD1149.";
RL Front. Microbiol. 8:2528-2528(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:POY76608.1}.
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DR EMBL; PJQD01000002; POY76608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S5BIK3; -.
DR STRING; 741276.A0A2S5BIK3; -.
DR OrthoDB; 4907at2759; -.
DR Proteomes; UP000237144; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd14483; SPX_PHO81_NUC-2_like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR24189; MYOTROPHIN; 1.
DR PANTHER; PTHR24189:SF50; MYOTROPHIN-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF03105; SPX; 2.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS51382; SPX; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000237144};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1..220
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REPEAT 423..455
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 456..488
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 525..552
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 595..627
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 870..1182
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
FT REGION 377..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1182 AA; 126348 MW; AA87216C085DDFDA CRC64;
MKFGKTLQQQ IFAQNGFPGW SSYFCDYKGL KKIINSLAKG RPADAALLAA GVRPPRPAAE
DSMPVEATTT EAQLFAHAST ANGGVVGEGP TTLLQAHKAA FFFKLERELE KINDFYYQRE
SALKVRLRTL IDKRKLLTAS LSDPDGKVKA LSRDSSSFGA LYEGFRNFER DLGRLQARRP
FLSLIETSQT YIELNATAFR KICKKWDKAC RRQADRFGET KPQQGQPDGQ LYLARQVEVQ
PVFNREFIAQ LADGAAGPTL TMGAAETDTA LNAAVASANL ISLENLVASD GARGSADGSS
IDGTGGAAPH LPTLFDRADR AEALEDLETA LVSAVKAGDR AIVDEVLGLL LPKKGDTAEH
GSPVARILWR AALEKPSSGA TTPVSSAPTT NGLEPTMNGV EKRPEPVTIS QDLLDFAFVD
DINGRTALHE AASAGRLPLV VACLDKGVSS AQADVYGRQP LHYAAMNGHA DVCRKLIEAG
ASPSTPDLDG YSPIIYSITN GWTAVVETFL AAGVTFETPT IGGADQLNAL SLACQYGHEA
IARLLLERGA QILPDPAGYW PQHLAAREGH DGVLRLLVEA FKGDSAPIDA QDKYSQSTPL
AHAASEGHTE SVKVLLAAGA DVHALDEFKR PAIHYAAWQG HVDCVNLLID SGATQPSAAA
RSDAADRDAA LATASTSTMD MDPLALDLDA DMIPDLSLPP PIIPFHIYGH AYLGDAKCLV
HVTLGHPNTT LPPFPAPVRL YDQPSHGHPP SLKLVITPRP DSSGTSIPHS VILPLADERE
VFSFQVDSLA DFSLEFDLFP TFGSKMIGKA VAVSSTFSDL KHQGSYVVPI VDPHLKVIGD
IPFEINVVKP FARAQLQIGG QFETYWKSTA TLNAGNPSAG GGAADQGPSV VTASSLSGEH
VRIVVQVTSD GHPVAWPQWK LPIEGLDVFV GDVTLDQLQS LAKRLGKSVD VSRVANAVDP
SVWYKAIADS LVSLEELLRI LPASLGVNLE IRYPTRSDIR RLGLARTIEV NDFVDSVLST
VYTSIQASAS GNGTSGDSSP SHRRIVLSSF NPVVCTALNW KQPNFSVFFA SYCGLSRTGN
AGGGLQYNQA GRLIPANRIE EDRRCTSIRE AVKFAKANNL LGVMLDATML VQIPSLIQSA
REHGLLITTF GTASRVLLAD AHMSDGVLSY ASSDFLKQTA AS
//
