ID   A0A2S5KKB7_9PROT        Unreviewed;       160 AA.
AC   A0A2S5KKB7;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=GDP-mannose mannosyl hydrolase {ECO:0000313|EMBL:PPC74959.1};
GN   ORFNames=C4K68_23595 {ECO:0000313|EMBL:PPC74959.1};
OS   Proteobacteria bacterium 228.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=2083153 {ECO:0000313|EMBL:PPC74959.1, ECO:0000313|Proteomes:UP000238196};
RN   [1] {ECO:0000313|EMBL:PPC74959.1, ECO:0000313|Proteomes:UP000238196}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=228 {ECO:0000313|EMBL:PPC74959.1,
RC   ECO:0000313|Proteomes:UP000238196};
RA   Krishnan R., Ramesh Kumar N.;
RT   "novel marine gammaproteobacteria from coastal saline agro ecosystem.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|PIRSR:PIRSR037599-3};
CC       Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR037599-3};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPC74959.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PRLP01000122; PPC74959.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S5KKB7; -.
DR   OrthoDB; 542521at2; -.
DR   Proteomes; UP000238196; Unassembled WGS sequence.
DR   GO; GO:0008727; F:GDP-mannose mannosyl hydrolase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd03430; GDPMH; 1.
DR   Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR   InterPro; IPR033715; GDPMH.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR020084; NUDIX_hydrolase_CS.
DR   InterPro; IPR000086; NUDIX_hydrolase_dom.
DR   PANTHER; PTHR43046; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR   PANTHER; PTHR43046:SF12; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   PIRSF; PIRSF037599; GDPMH; 1.
DR   SUPFAM; SSF55811; Nudix; 1.
DR   PROSITE; PS51462; NUDIX; 1.
DR   PROSITE; PS00893; NUDIX_BOX; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:PPC74959.1};
KW   Magnesium {ECO:0000256|PIRSR:PIRSR037599-3};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|PIRSR:PIRSR037599-3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000238196}.
FT   DOMAIN          15..155
FT                   /note="Nudix hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS51462"
FT   MOTIF           52..73
FT                   /note="Nudix box"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037599-4"
FT   BINDING         51
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037599-3"
FT   BINDING         71
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037599-3"
FT   BINDING         124
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR037599-3"
SQ   SEQUENCE   160 AA;  18350 MW;  FA180CB7448188B5 CRC64;
     MAQRLSTTQF AAVIRNTPLI SIDLIVRNKA NQVLLGQRLN RPAQGYWFVP GGRIFKNERL
     ADAFARLTRE ELGSEMKIEQ ANLLGVFEHL YEDCVFGDQT TTHYVVTGME LQLEHDLDDL
     PCAQHDHYRW FDQTLLLSAD DVHTNTKAYF VPSEGIRVSR
//