ID   A0A2S5KTD6_9PROT        Unreviewed;       844 AA.
AC   A0A2S5KTD6;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Bifunctional diguanylate cyclase/phosphodiesterase {ECO:0000313|EMBL:PPC78010.1};
GN   ORFNames=C4K68_07085 {ECO:0000313|EMBL:PPC78010.1};
OS   Proteobacteria bacterium 228.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=2083153 {ECO:0000313|EMBL:PPC78010.1, ECO:0000313|Proteomes:UP000238196};
RN   [1] {ECO:0000313|EMBL:PPC78010.1, ECO:0000313|Proteomes:UP000238196}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=228 {ECO:0000313|EMBL:PPC78010.1,
RC   ECO:0000313|Proteomes:UP000238196};
RA   Krishnan R., Ramesh Kumar N.;
RT   "novel marine gammaproteobacteria from coastal saline agro ecosystem.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPC78010.1}.
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DR   EMBL; PRLP01000021; PPC78010.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S5KTD6; -.
DR   OrthoDB; 5293040at2; -.
DR   Proteomes; UP000238196; Unassembled WGS sequence.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR012226; Diguanyl_cyclase/Pdiesterase.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF13188; PAS_8; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   PIRSF; PIRSF005925; Dos; 2.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000238196}.
FT   DOMAIN          123..193
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          196..248
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          442..574
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          583..837
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   844 AA;  93524 MW;  9E5BC776AACF845E CRC64;
     MPTQLPDLFA STLEQLSDAV MVTDGHGVLL FNTAAERFWD CPRQTALAQP LAALWPADLP
     AVHELSTAPQ DINLTVAGIV RRGRLRVSRA EQQGQTIFTV FISALDSHLR QTASASGYGN
     AEHLQLLSMV TDRTDNAIII TDGRWRTLYI NDGFSQMFGY SSKQMLGAIP TSIIAPYAEQ
     EQVDALHDQL ARGQPFHAEE LIYTRDGKRI WCSVTTNPVL DEQGQLLNTL TVLTDITQSK
     MHELLQNRVL SAMVREEPLE TVMNTVCREV EHLAPEVTAS ILRVDEQGRL HPLAGPSLPA
     EYNKALEGVA IGEGVGSCGT AAFIGEPVIV TDIASHPYWA PYKQLALPHG LKACWSTPIR
     SSSGRILGTF AFYYRECRGP NPLHQRMVEV STHLCALALE REEARAHIRQ LAFYDSLTKL
     PNRSLLHARA DQALAAAERH RDNIAVLFID LDRFKQVNDS LGHPAGDELL RVIAQRLTEN
     LRHVDIVGRL SGDEFVMVLP RYSSQALAEV VEQLKGRISQ PFSIGSTTLI PSASIGISLF
     PNDGHDMESL IHRADMAMYQ AKSMGRGHVS YFSHELNEQA QQRMALENAL RDALDNGGLQ
     LHYQPQINLA DGSLYGVEAL ARWQHPELGS IPPTRFIPLA EECGLIGQLG HWAVQEACRQ
     LAAWRRQGLQ VPAVSVNLSP SDFHNLELPQ QIAHTLQHHQ LQPQDLTLEI TESVLMDTHP
     STLTTLDAIH SQGVNLAMDD FGTGYSSLSY LRRLPIHELK LDRSFVSDLE SDATARALSE
     AVMRIGESLR LIVVAEGIEE EGQQQILRQQ GYQVGQGYLF SRPVPAAELQ QWLQQWRAAA
     VSHG
//