ID A0A2S5RGP6_9MOLU Unreviewed; 503 AA.
AC A0A2S5RGP6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335,
GN ECO:0000313|EMBL:PPE06468.1};
GN ORFNames=MCORR_v1c00960 {ECO:0000313|EMBL:PPE06468.1};
OS Mesoplasma corruscae.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales;
OC Entomoplasmataceae; Mesoplasma.
OX NCBI_TaxID=216874 {ECO:0000313|EMBL:PPE06468.1, ECO:0000313|Proteomes:UP000239785};
RN [1] {ECO:0000313|EMBL:PPE06468.1, ECO:0000313|Proteomes:UP000239785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ELCA-2 {ECO:0000313|EMBL:PPE06468.1,
RC ECO:0000313|Proteomes:UP000239785};
RA Lo W.-S., Kuo C.-H.;
RT "Genome sequence of Mesoplasma corruscae ELCA-2 (ATCC 49579).";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPE06468.1}.
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DR EMBL; PHNF01000001; PPE06468.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S5RGP6; -.
DR OrthoDB; 9803205at2; -.
DR Proteomes; UP000239785; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR35795:SF1; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE, SYMMETRICAL; 1.
DR PANTHER; PTHR35795; SLR1885 PROTEIN; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Membrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000239785};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}; Transmembrane {ECO:0000256|HAMAP-Rule:MF_00335};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00335}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00335"
FT DOMAIN 319..412
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 88..129
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 503 AA; 57792 MW; 866272D2051D6D32 CRC64;
MIFIVLMIIF IIFFIITLSL LLYIMFSTSQ KHLIVKKKEK ANKERKQILS DTYREINQEK
KLFNENCYLE HQKHEIAQKN IAEQEKVLNQ LKTFYNQQKK QLDEKEIKLQ KLKEKLILKQ
EELTTKLQNL SEFTQEEAKE EILKNVENKI QHEIISRIKK AENFANSRSK ELSNDIILSA
MEKFKTDIVN EKTTSVVKLE NDDLKGWIIG KDGRNTKAFE NYGGVEIIVD DTPKVVTVSC
FNPIRREIAT RTLYKLLKEK KIQPIRIEKE LKIQEELLEE NILEIGYQTV NELNILDMDK
NLVKLLGRLK YRTSYGQNVL LHSVEVAKIA STIASELGLS AKTALRAGLL HDIGKALDFE
REGSHVTLGV EQASKYGENE IVQNAIASHH NDVAKESEIA IIVSIADAIS ASRPGVRNDT
IENFFVRMNQ IEEIGQEIPG IAKTYAFQSG RQIRIIIDPI ASNESEMFEI LETFKNNLKD
KVVIPGEITI TAIREKREVV IIN
//
