ID A0A2S5ST32_9BURK Unreviewed; 1101 AA.
AC A0A2S5ST32;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=C1704_11350 {ECO:0000313|EMBL:PPE65898.1};
OS Caldimonas caldifontis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Caldimonas.
OX NCBI_TaxID=1452508 {ECO:0000313|EMBL:PPE65898.1, ECO:0000313|Proteomes:UP000238605};
RN [1] {ECO:0000313|EMBL:PPE65898.1, ECO:0000313|Proteomes:UP000238605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCRC 80649 {ECO:0000313|EMBL:PPE65898.1,
RC ECO:0000313|Proteomes:UP000238605};
RA Tang B.;
RT "Reclassifiation of [Polyangium] brachysporum DSM 7029 as Guopingzhaonella
RT breviflexa gen. nov., sp. nov., a member of the family Comamonadaceae.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPE65898.1}.
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DR EMBL; PSNX01000010; PPE65898.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S5ST32; -.
DR OrthoDB; 5905204at2; -.
DR Proteomes; UP000238605; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000238605}.
FT DOMAIN 18..484
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 520..791
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT REGION 531..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 39..46
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 1101 AA; 120227 MW; 3813D3055AAFF6C7 CRC64;
MRISGPGPQA AYRIDGRLVG RDEFYAQACD PRRSVVVEAC AGAGKTWMLV SRILRALLDG
VPAREILAIT FTKKAAAEMR GRLMEWLGDL ALADEGARVQ ALVDRGLSPE DARARAGDLA
GLYERLLASG EQVEVRTFHA WFAQLMRAAP LQWLERLGLA PEAQLLEDTS ELQGPAWREW
LDRVHADPAL REDLAALMRE HSGSRVREWL LGLIDKRVEF ALADAAGSLA ASVPSAAQWR
PAFAGLDHPA QRLRHPAVTD TLRAVARSLG AQDKGTARKA AQALEEALSL EDDAAALAAA
RSALLTTNGS VRKHLEAPGL EEAAAWLDEI QQGMAQETAH REHQRLTRLG RVLLEVYEAI
KRRRGLADMA DLERCALALL GNDSLAAWMQ ERLDARVSQV LIDEFQDTNP LQWQALSHWL
SSYAGASGGA SGQRPPGVFI VGDPKQSIYR FRRAEPRVFE AAKDLVVRGL GGSVLACDHT
RRNAAGVIDA VNAVFLAAQA EAAYSGFRAH TTERHDDVVR GGIWALPRVE RPERGAREAG
EPGWRDSLSQ PRHEAQEPWR AQEARLVADA IVQLVRGDGV APADIQVLAR RRAPLAGVAQ
ALRERHIPCA SPEDHALLDA LEVRDLVALL DALVSPGHAL SLAQALRSPI FDATDEDLVG
LAQRARELGS WWAALTHEGP GGWPSEPLRR AARLLPAWAE AARHLPPHDL LDRIYADGDV
LARYARRVPP ELRESVRLHL EALLAWSLEL DGGRYASPHQ FVHALRRRSP RVSLGSVPDA
VQLLTVHAAK GLEARVVFVI DTDPDRRSSA DRHDSATVLV DWVADEAHPR CFAFVASERN
VAPSLEAAMA IERAERAREA MNGLYVAMTR ARERLIVSAS APHNGQNGPS WWSRLSAVSE
AWVQRQEASP AAQAAPGAVE VWRLPSLQRP AVSPGPVLAP ERGAGARLGE VVHRCLEWLA
GPEGPAFERI DELARAAAEA HSADDAMARA AAQIVRRMAS DPTIGALLGA EPVAWAGNEV
PVVTDGRPGR IDRLVLQHTA DGEQWWVLDY KIETHPDTDP ALVAQLERYR HAIRRADPQR
LVRAAFITGD GRLIEVIDSA K
//
