ID A0A2S5SZS5_9BURK Unreviewed; 2210 AA.
AC A0A2S5SZS5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:PPE68261.1};
DE Flags: Fragment;
GN ORFNames=C1702_18050 {ECO:0000313|EMBL:PPE68261.1};
OS Caldimonas thermodepolymerans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Caldimonas.
OX NCBI_TaxID=215580 {ECO:0000313|EMBL:PPE68261.1, ECO:0000313|Proteomes:UP000239406};
RN [1] {ECO:0000313|EMBL:PPE68261.1, ECO:0000313|Proteomes:UP000239406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15344 {ECO:0000313|EMBL:PPE68261.1,
RC ECO:0000313|Proteomes:UP000239406};
RA Tang B.;
RT "Reclassifiation of [Polyangium] brachysporum DSM 7029 as Guopingzhaonella
RT breviflexa gen. nov., sp. nov., a member of the family Comamonadaceae.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPE68261.1}.
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DR EMBL; PSNY01000038; PPE68261.1; -; Genomic_DNA.
DR Proteomes; UP000239406; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd05931; FAAL; 1.
DR CDD; cd19531; LCL_NRPS-like; 2.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR040097; FAAL/FAAC.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000239406}.
FT DOMAIN 598..675
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1651..1726
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 676..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..692
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 2210
FT /evidence="ECO:0000313|EMBL:PPE68261.1"
SQ SEQUENCE 2210 AA; 242049 MW; 6E29A6C6FFA862ED CRC64;
MPPPEVDTLA ALLLWRCEQH PHDLAYAYVR DTLEQDARWT YAELLQQART AAAHIAARTR
PGDRVLLAHP AGLAFVRDFW GCVLSGRIAV PVPAPDPVRA KNSLPRLQAI IDDAEATLVL
TTADLLPAAA QAPGPTPWCA LDGLDPLPQA DADPAVTPHD VAYLQYTSGS TSAPRGAILT
HANVVAQCRG AVAALAMDRD SRALCWLPQH HDYGLVSGLL WPLHAGAASY LMSPLTFLRR
PLRWLDAIGH FGITHTGAPN FAYAACTRAL QQAPSWRGRL DSLLSATCGA EPIQHETIRR
FEAAFGPHGW RRTAFAAGYG MAETVLTVTL KPADGVQRVE ACDAEALAAG RAEPARPGRP
ARLVMGCGRA IDGMEMRIVD PKTRRECAAR QVGEIWVRGS SVGRGYWRQA QDGPNSFDAR
TAKGAGPFLR TGDLGFVDDG ELFVTGRLKD LIIIRGRNHY PQDIEWTAQR THAALRQGYG
AAFAIEGPDA ENGERLVLVQ ELERRVAAPD LPAIAAGIRR AIAEEHDLPV HAIALVRSGS
VPRTSSGKIR RSSCKQDYLA GRLEILHLDL QAEAEAAPDQ DDAALLATLR AEVEASPDRE
AALGRAIRRL AARLLRRDPQ DVPLDANLFE AGLDSLSTFR LAHQLEQLLD RELPPGLLLQ
QPNLGHLAHA LAAPAPVTEP ARPEPPLAPP ASRQPLSATQ EGVWFVERLA GPSAMYNIAQ
ALHIDGPLDM AALQRSLQAL VARHDALRTG LQDLDGVPTQ TVTPAIDLPL PVTELPPDTT
GQALQRLLEQ HAREPFDLAW PPLLRARLFR LDARRHVLLL VVHHLVADGW SMGVIARELG
RLYAAHVQGE VPSLPAATPY GAFVRWQREH LDQGAALADI EHWRERLAGL QPLELPTDHP
RPPRPSHAGG MVTLELPEPL VRQLRTLARD EGASLFMVLL AVFKTLLMRY TGQDDIAVGS
PVAARLRPEF QDTVGFFSNT LVLRTDLGGD PGFRELLARV RATALDAYAH QSLPSDKLVA
ALGLPRDPSR NALYQVAFAL QNMPDLAMAL EGAKVSPLPL HTGTAKIDLW ASFFETDGAL
RGEFEYSRDL FEPDTIERLA RHYRHLLEAV VRDPAQPVSR LPLLDEVEWR QIVHEWNATS
RPYPLELGVH QLFGQIAREH PHALAARFDG QELSYAELDR LSNQAAHLLA AHGVAPGSLV
AVAMERSLEL VVALMAVLKA GAAFVPLDPD YPAERLAFML QDSAPSALLT QPHTRERLPA
TAIPAVVLDG WQLLQDQPTQ PPAVTTRPDD LAYVIYTSGS TGQPKGALLT HKGLTNHILW
LRETLRLDAG DRVLQKTSIS FDAAIWEFFT PLAAGAAVVL ARPGEHLDTG ALVRTLEAES
ITAVQMVPSA LRALLDEPGL SRCTRLRHLI SGGEALERGL AREVLQRLPG VTLGNFYGPS
EASDDATHYE LTAPPEGPGL VPIGKPIANV RCHILDAHGQ PVPIGVPGEL YIGGAGVGRG
YLGREALTAE RFVPDPFHPG ERLYRTGDRA RYLRDGHIEF LGRLDAQVKL RGFRIELGEV
EAALNACEGV QHSAVVLRED RPGQPQLVAY VVAPGVDPAA LRARLQARLP HYMVPAAFVG
LDALPRLPNG KLNRRALPAP APQAEDAARV APRNPVEQIL WDIWRDVLGH GDFGVHDGFF
ELGGHSLQAT QVVSRVRQVM QAELPLRALF EAPTIARLAR LLDAPERARA LLPAIERVPR
DGPLPVSFSQ RRMWLVQQMA PHSTAYNMPC AVRLRGRLDR AALQRALDAL VERHEAFRTT
LELVGSEPMQ FIHPPQPVAI TEADFSHLPA DQRERQVAAW LGEQAGVPFD LARYPLHRTF
LARLDEDDHV MMWLAHHAIG DQWSGMVLLR EFAALYQPGK ATLQKLPAPE IGYVDYAVWQ
RRHFDGAALA GQLEYWRRQL AGIEPLALPF DRPRPAQPSF RGSHAMVELS PQTRVALQRF
SARHGATPFM TLLACFQLLL ARYTGGDDIA VGTPIANRTH YQSEHLIGTL VNTLVMRTSL
ADPISFTELL ARVRSTALDA YAHQDIAFDH LVEVLEGNRQ SEHPLNVSVL FNVLNAPMGQ
LRLDGLTPQP FDFDRGSAQF DLSLHVDTEV TGRAYLEYST DLFLPETAQR LLDNYVLLLE
QVLADPGQPV TAYRLCTDAE RAQLARWNDT GMGYDPAAAT IPQLLAGPVQ
//
