ID   A0A2S5TGS4_9GAMM        Unreviewed;       575 AA.
AC   A0A2S5TGS4;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=3-oxosteroid 1-dehydrogenase {ECO:0000313|EMBL:PPE74174.1};
GN   ORFNames=C3942_09065 {ECO:0000313|EMBL:PPE74174.1};
OS   Solimonas fluminis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Nevskiales; Nevskiaceae;
OC   Solimonas.
OX   NCBI_TaxID=2086571 {ECO:0000313|EMBL:PPE74174.1, ECO:0000313|Proteomes:UP000238220};
RN   [1] {ECO:0000313|EMBL:PPE74174.1, ECO:0000313|Proteomes:UP000238220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HR-BB {ECO:0000313|EMBL:PPE74174.1,
RC   ECO:0000313|Proteomes:UP000238220};
RA   Lee Y., Jeon C.O.;
RT   "Genome sequencing of Solimonas sp. HR-BB.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPE74174.1}.
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DR   EMBL; PSNW01000004; PPE74174.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S5TGS4; -.
DR   OrthoDB; 9813348at2; -.
DR   Proteomes; UP000238220; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008202; P:steroid metabolic process; IEA:UniProt.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   PRINTS; PR00411; PNDRDTASEI.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000238220}.
FT   DOMAIN          9..546
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   575 AA;  62599 MW;  9B57F7E5A1871080 CRC64;
     MSNFDQQFDV VVVGSGGGGM TAALCAQSLG LSAVVIEKSD KYGGTSAVSG GGIWIPNNDD
     IARTGGSDSY EEGLTYLKEI VGSEVPQERI EAYLKNAPEM VRYMAKTFGV KYRNVPKYPD
     YYSNRPGGKD GWRSMEPVDF DASLLGPEFD RQRESFKGTL LMGRIAMSQV EAHTLFSRGP
     GWIWLTLKML LKYWLDLGWR RRTHRDRRQV LGQGMVSALR YAMLQKNVPL VLECGMDSLI
     EENGRVVGVN VVHRGRKQRY GARRGVILAC GGFESNQAMR EKYLAQPTKV EWTAAPPINQ
     GDGIRAGQAL GAATKLMDKV WGSPTVRKPG ADQQITLFIE RGMPGCVAVN AKGKRFANEA
     AAYPDFRDAM YADHAKGNGC VPAWLVFDAT FRYKYPMGIF LPGQIEPDAR LPADWLDKVY
     FRADSIDALA GKIGVDRKGL AETVARMNEY AKTGVDPEFG KGSIPIDRYY SDPSVKPNTC
     LGPIVKPPFY AVPMYPGEIG TKGGLDVDPR ARVLREDGSV IAGLYAIGNT SAAVMGSTYP
     GAGSTLGPAM TFGYIAARDI AESAKAEQPR IAAAA
//