ID A0A2S5VYN2_9MICO Unreviewed; 332 AA.
AC A0A2S5VYN2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Flap endonuclease {ECO:0000313|EMBL:PPF76568.1};
GN ORFNames=C5B96_16540 {ECO:0000313|EMBL:PPF76568.1};
OS Subtercola sp. Z020.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Subtercola.
OX NCBI_TaxID=2080582 {ECO:0000313|EMBL:PPF76568.1, ECO:0000313|Proteomes:UP000238959};
RN [1] {ECO:0000313|EMBL:PPF76568.1, ECO:0000313|Proteomes:UP000238959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z020 {ECO:0000313|EMBL:PPF76568.1,
RC ECO:0000313|Proteomes:UP000238959};
RA Davis E.W.II., Tabima J.F., Weisberg A.J., Lopes L.D., Wiseman M.S.,
RA Wiseman M.S., Pupko T., Belcher M.S., Sechler A.J., Tancos M.A.,
RA Schroeder B.K., Murray T.D., Luster D.G., Schneider W.L., Rogers E.,
RA Andreote F.D., Grunwald N.J., Putnam M.L., Chang J.H.;
RT "Bacteriophage NCPPB3778 and a type I-E CRISPR drive the evolution of the
RT US Biological Select Agent, Rathayibacter toxicus.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPF76568.1}.
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DR EMBL; PSTT01000131; PPF76568.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S5VYN2; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000238959; Unassembled WGS sequence.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000313|EMBL:PPF76568.1};
KW Hydrolase {ECO:0000313|EMBL:PPF76568.1};
KW Nuclease {ECO:0000313|EMBL:PPF76568.1}.
FT DOMAIN 3..275
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 332 AA; 34272 MW; 4EE8D000BAE3AA6F CRC64;
MTGRLMLLDT ASLYFRAFHG VPDTVRSPDG SPVNAVRGLL DMIAKLVADF SPTSLVACWD
DAWRPSWRVD LIPSYKEHRV ARVVPGGLDV EEVPPLLTQQ IPLIREVLEA FGIVVLGAPD
MEADDVIGTL ATHADGPVDV VTGDRDLFQL VDDQAPVRVI YTARGMSRLE LVTADVLTTK
YGITPSQYVD FAVMRGDPSD GLPGVAGIGE KTAATLLAEH GDLAGILAAA GASPSPLSAS
VRAKLTAAAD YLVVAPRVVE VVRDLAVAVP PAAGPGAAAT SPGAAAAHPA AAPDARLGAL
SPERLEAVHA LAGKWGLGGS ADRAIRALAA AG
//
