ID A0A2S5W7F0_9MICO Unreviewed; 721 AA.
AC A0A2S5W7F0;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ATP-dependent chaperone ClpB {ECO:0000313|EMBL:PPF89750.1};
GN ORFNames=C5B96_00645 {ECO:0000313|EMBL:PPF89750.1};
OS Subtercola sp. Z020.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Subtercola.
OX NCBI_TaxID=2080582 {ECO:0000313|EMBL:PPF89750.1, ECO:0000313|Proteomes:UP000238959};
RN [1] {ECO:0000313|EMBL:PPF89750.1, ECO:0000313|Proteomes:UP000238959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Z020 {ECO:0000313|EMBL:PPF89750.1,
RC ECO:0000313|Proteomes:UP000238959};
RA Davis E.W.II., Tabima J.F., Weisberg A.J., Lopes L.D., Wiseman M.S.,
RA Wiseman M.S., Pupko T., Belcher M.S., Sechler A.J., Tancos M.A.,
RA Schroeder B.K., Murray T.D., Luster D.G., Schneider W.L., Rogers E.,
RA Andreote F.D., Grunwald N.J., Putnam M.L., Chang J.H.;
RT "Bacteriophage NCPPB3778 and a type I-E CRISPR drive the evolution of the
RT US Biological Select Agent, Rathayibacter toxicus.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homohexamer. The oligomerization is ATP-dependent.
CC {ECO:0000256|ARBA:ARBA00026057}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPF89750.1}.
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DR EMBL; PSTT01000007; PPF89750.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S5W7F0; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000238959; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}.
FT DOMAIN 53..198
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 454..622
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 621..712
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT COILED 267..347
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 721 AA; 79430 MW; BA2339E9DF86064A CRC64;
MQPQSGQQNV DEQSALEKYG VNLTKIAASG KLDPVIGRDA EIRRVSQVLT RRTKNNPVLI
GEPGVGKTAV VEGLAQRIVA GDVADSLKGK QLVSLDLAAL VAGAKYRGEF EERLKAVLQE
INDADGEIIT FVDELHTLMG AGGGEGSVAA SNMLKPMLAR GELRLIGATT LNEYREYIEK
DAALERRFQQ VFVGEPSVED TIAILRGLKE RYEAHHKVAI ADAALVAAAS LSNRYISGRQ
LPDKAIDLID EAASRLRMEI DSAPVEIDEL RRSVDRLRLE ELALKKEKDD ASKQRLEKLR
DDLATRSADL EVLQERWDRE RAVLNRVGEL KTQLDAARMS AEKAQREGNL ERASKLLYGE
IPVIERQLRE AESAEQYPDG ERMVSDQVTE AEIAAVIAAW TGIPVDRLTQ GETQKLLNLE
KELGKRLIGQ RPAVRAVADA VRRTRAGISD PNRPTGSFLF LGPTGVGKTE LAKALAEFLF
DDERAMIRID MSEYGEKHSV ARLLGAPPGY IGYEQGGQLT EAVRRRPYSV VLMDEVEKAH
PEVFDVLLQV LDDGRLTDGQ GRTVDFRNTI LILTSNLGSQ FLVDPTLSDD AKEAAVLQVV
RQAFKPEFVN RLDDIVVFTA LTHDDLAQIV SLYVDRLARR VSERGLSLAV TPDARSWLAD
KGYDPAYGAR PLRRLMQREI DDRLSMALLS GAIRDGDTVY VGLDPDGTAL TVGPVVLVPE
D
//
