ID A0A2S6GHU5_9PSEU Unreviewed; 400 AA.
AC A0A2S6GHU5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=AcrR family transcriptional regulator {ECO:0000313|EMBL:PPK64731.1};
GN ORFNames=CLV40_118121 {ECO:0000313|EMBL:PPK64731.1};
OS Actinokineospora auranticolor.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=155976 {ECO:0000313|EMBL:PPK64731.1, ECO:0000313|Proteomes:UP000239203};
RN [1] {ECO:0000313|EMBL:PPK64731.1, ECO:0000313|Proteomes:UP000239203}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YU 961-1 {ECO:0000313|EMBL:PPK64731.1,
RC ECO:0000313|Proteomes:UP000239203};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPK64731.1}.
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DR EMBL; PTIX01000018; PPK64731.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S6GHU5; -.
DR OrthoDB; 4456617at2; -.
DR Proteomes; UP000239203; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 2.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041490; KstR2_TetR_C.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF250; TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)-RELATED; 1.
DR Pfam; PF17932; TetR_C_24; 1.
DR Pfam; PF00440; TetR_N; 2.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000239203};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 18..78
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DOMAIN 218..278
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 41..60
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT DNA_BIND 241..260
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 43825 MW; 79DB71ECC5817503 CRC64;
MSRQEARLTS GAPVRRPRDR KAQLARAAAE LFGRRGYHAV GVNDIAAAAG VTGPALYRHF
QNKQDVLGYV LLTGVDKLTV RVCTAVEGVE NDPERGLRPL LEAAAEVSIE ERALTALWRW
QGRHLHAGDQ KEIRRRVGAL LAQWLKGLRA LRPELDDGAA DVICFAALSV FGSVGDHHAT
LPTPEFTRLL ARLGETVVRT PLPTEQAPTV WRTRAPAPTR REELLTAATR LFRDRGFHAV
SMEDIGAAAG IAGPSIYRHF TSKSDILLAA SRRMADRLRL GLDNSLATAT NAEDALRRLV
RSYVDTVLRS DDLIAVYTAE LVNLPERDGK ELRVLQREYV TEWVRLLREV RPGMSDPAAR
VVVHAALTIV NDLPRTGRVN GRATLAAELA ALAAAVLVAD
//
