ID   A0A2S6GM55_9PSEU        Unreviewed;       391 AA.
AC   A0A2S6GM55;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Threonine dehydrogenase-like Zn-dependent dehydrogenase {ECO:0000313|EMBL:PPK66260.1};
GN   ORFNames=CLV40_111224 {ECO:0000313|EMBL:PPK66260.1};
OS   Actinokineospora auranticolor.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=155976 {ECO:0000313|EMBL:PPK66260.1, ECO:0000313|Proteomes:UP000239203};
RN   [1] {ECO:0000313|EMBL:PPK66260.1, ECO:0000313|Proteomes:UP000239203}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YU 961-1 {ECO:0000313|EMBL:PPK66260.1,
RC   ECO:0000313|Proteomes:UP000239203};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPK66260.1}.
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DR   EMBL; PTIX01000011; PPK66260.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S6GM55; -.
DR   OrthoDB; 241504at2; -.
DR   Proteomes; UP000239203; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239203};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          27..151
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          198..268
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   391 AA;  42289 MW;  818F61AB5FBB1E77 CRC64;
     MRANTWAGRN KVEVRDVPDP RILNSRDAIV RITSTAICGS DLHLVDGYVP TMQDGDVLGH
     EFMGEVIEVG PGVARDRLSV GDRVVVPFPI ACGACAACAA ELYSCCENTN PNAGIAEKMF
     GHPVAGIFGY SHLTGGYAGG QAQYARVPFA DVNPLRIESD LTDEQVLFLS DILPTGYMGA
     EMCDIQPTDV VAVWGAGPVG QFAMDSARVL GAARVIAIDK EPYRLRMAEQ AGHTPVNFEE
     VDVRSALLEL TGGRGPDKCI DAVGMEATHG SAHIAAYDRL KQAVRSETDR PHALRQAITS
     CRSGGVVSVI GVYGGLLDKF PAGAWMNRSL TLRTGQCHVQ RYMKPLLARI ERGEIDPTRI
     ITHTLPLDEA DRGFEIFKNK EEDCEKVVLK P
//