ID   A0A2S6H175_9PSEU        Unreviewed;       104 AA.
AC   A0A2S6H175;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Quaternary ammonium compound-resistance protein SugE {ECO:0000313|EMBL:PPK71239.1};
GN   ORFNames=CLV40_101428 {ECO:0000313|EMBL:PPK71239.1};
OS   Actinokineospora auranticolor.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinokineospora.
OX   NCBI_TaxID=155976 {ECO:0000313|EMBL:PPK71239.1, ECO:0000313|Proteomes:UP000239203};
RN   [1] {ECO:0000313|EMBL:PPK71239.1, ECO:0000313|Proteomes:UP000239203}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YU 961-1 {ECO:0000313|EMBL:PPK71239.1,
RC   ECO:0000313|Proteomes:UP000239203};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): from individual species to whole genera.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC       {ECO:0000256|RuleBase:RU003942}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PPK71239.1}.
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DR   EMBL; PTIX01000001; PPK71239.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S6H175; -.
DR   OrthoDB; 21828at2; -.
DR   Proteomes; UP000239203; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   PANTHER; PTHR30561:SF0; GUANIDINIUM EXPORTER; 1.
DR   PANTHER; PTHR30561; SMR FAMILY PROTON-DEPENDENT DRUG EFFLUX TRANSPORTER SUGE; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239203};
KW   Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        33..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   104 AA;  10523 MW;  C4914A3167638726 CRC64;
     MAWVVLVVSG LFETVWAVAL GASRGFSRLV PSVVFAVALV VSMSGLAYAL RAVPVGTGYA
     VWVGIGAVGT AVYGMVALAE PVAVGRVLCL VLIVAGVVGL KVLH
//