ID A0A2S6IC83_9ACTN Unreviewed; 565 AA.
AC A0A2S6IC83;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Putative peptidoglycan lipid II flippase {ECO:0000313|EMBL:PPK90861.1};
GN ORFNames=CLV92_12237 {ECO:0000313|EMBL:PPK90861.1};
OS Kineococcus xinjiangensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Kineococcus.
OX NCBI_TaxID=512762 {ECO:0000313|EMBL:PPK90861.1, ECO:0000313|Proteomes:UP000239485};
RN [1] {ECO:0000313|EMBL:PPK90861.1, ECO:0000313|Proteomes:UP000239485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22857 {ECO:0000313|EMBL:PPK90861.1,
RC ECO:0000313|Proteomes:UP000239485};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPK90861.1}.
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DR EMBL; PTJD01000022; PPK90861.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S6IC83; -.
DR OrthoDB; 4350032at2; -.
DR Proteomes; UP000239485; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR InterPro; IPR004268; MurJ.
DR PANTHER; PTHR47019; LIPID II FLIPPASE MURJ; 1.
DR PANTHER; PTHR47019:SF1; LIPID II FLIPPASE MURJ; 1.
DR Pfam; PF03023; MurJ; 1.
DR PRINTS; PR01806; VIRFACTRMVIN.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Reference proteome {ECO:0000313|Proteomes:UP000239485};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 54..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 542..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 56147 MW; 8E576A7F612FDF0E CRC64;
MRPVRTLAAA AVTVAAITVL ARVAGFGRVV VFSDAVGDNC LGDVYNTANL VPNVLFEVVA
GGMLAGALVP VLAGPLAAGT AEGRERASRT ASAVLTWAVL ALVLVAVLTA VLARPVADLL
LQDKGTECPG ALPLAVGMLY VFLPQVPLYG VAVVLGGALQ AQRRFTASAV APLASSLVVM
AAYAVFAAAL PGGTDLASAP LSSLPGGALA VLTWGTTLGV LAMALTHAPA LRSQIRWRPA
LRPAPGDGAA LRRLALAGLT ILFAQQAVAV TAVALANDRA AGSVTQWGWA WTLFLLPYAV
LAVPVATAVF PRLAAASGPR APDLAALLAS TARLVTLASA AGAAGLAAAA LPIAAFFLLG
DGSPGDPGDL ATALVVFAPA LLGYGLTALL VRTLYAVGRG RAAAVAATAG WLLVLGAAPL
LVLALPPERV VTALALAHTL GLTLAGVLLV IAVRRACGVA ALAGLPRAVL AGAVAALLAG
GAGHGVASVL PLATTSQALV AGVVAGAVAG LLWLAVVALL DRRDVAALAG RFARVLPVRG
ARAPRAEGAQ PDERDGSHEQ DGSRR
//
