ID A0A2S6IVN3_9ACTN Unreviewed; 356 AA.
AC A0A2S6IVN3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=DNA-binding LacI/PurR family transcriptional regulator {ECO:0000313|EMBL:PPK98422.1};
GN ORFNames=CLV92_101117 {ECO:0000313|EMBL:PPK98422.1};
OS Kineococcus xinjiangensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kineosporiales; Kineosporiaceae;
OC Kineococcus.
OX NCBI_TaxID=512762 {ECO:0000313|EMBL:PPK98422.1, ECO:0000313|Proteomes:UP000239485};
RN [1] {ECO:0000313|EMBL:PPK98422.1, ECO:0000313|Proteomes:UP000239485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22857 {ECO:0000313|EMBL:PPK98422.1,
RC ECO:0000313|Proteomes:UP000239485};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): from individual species to whole genera.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PPK98422.1}.
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DR EMBL; PTJD01000001; PPK98422.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S6IVN3; -.
DR OrthoDB; 4268837at2; -.
DR Proteomes; UP000239485; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:PPK98422.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000239485};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 24..78
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 37359 MW; AF9C37284057ADD0 CRC64;
MTDTGAPEDG RGTAPGPGGP RKRPTIRDVA REAGVSYGTV SRVLNDRDWV SPEAARAVKA
AIARTGYTTN HHARSLATGR SGSIAFLLTE PQHLLFEDPN FSILLRGVAQ ALSRRELTLV
LMIAGTPDER GRVLTYLSGG HVDGVLLVSS HAGDPLLDEL VAAEVSVVAC GRPLGHEEQM
ASVAADDRAG ARAAVRHLLG TGRRRIATIT GPLDTSGGVD RLSGYRDALE AAGAGYREDL
VAHGDWGRES GAEAMRSLLA ADPELDAVFV ASDLMAAGAL ATLREGDRSV PADVAVVGFD
DSGLAATLDP PLTTVRQPLE RISEEMVRLL TESFSGQRPL SVTVPTELVV RESAPG
//
