ID A0A2S7NP23_9HELO Unreviewed; 855 AA.
AC A0A2S7NP23;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=DUF221 domain-containing protein {ECO:0000313|EMBL:PQE03761.1};
GN ORFNames=CJF30_00006461 {ECO:0000313|EMBL:PQE03761.1};
OS Rutstroemia sp. NJR-2017a BBW.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Rutstroemiaceae; Rutstroemia.
OX NCBI_TaxID=2070414 {ECO:0000313|EMBL:PQE03761.1, ECO:0000313|Proteomes:UP000238072};
RN [1] {ECO:0000313|EMBL:PQE03761.1, ECO:0000313|Proteomes:UP000238072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJR-2017a BBW {ECO:0000313|EMBL:PQE03761.1,
RC ECO:0000313|Proteomes:UP000238072};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PQE03761.1}.
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DR EMBL; NJPT01000094; PQE03761.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S7NP23; -.
DR Proteomes; UP000238072; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF26; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000238072};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 582..604
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 676..693
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..168
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 191..383
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 395..667
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 753..847
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT REGION 720..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 855 AA; 94942 MW; FDCB30969A16CAEF CRC64;
MSDTAKQVSS SLSALVATLV PTLIVAAVYF LIFLILRRSN VRWYAPRTYL GALREQERTK
PLPSGFFNWI GPFAKIPDLY ALQHQGLDAY LFLRFLRMTV VIMFVGCCIT WPVLFPINAT
GGGGAQQLDI LSISNISVKS QSGKDRYYAT CFIGWIFFGF VLFLVTRETI FYVNLRQAFL
LNPVCANRIS SRTVLFISVP APFLDEGKLR KIFGTSVRNV WITADTEKVD ELVEQRDKIA
FKLESAEVKL IKEANGARLK AIKNGASQDE LPVIEGEGES GSMASRWIPQ KKRPTHKLGK
FGLYGKKVDT IDWARSQLET LIPETEAAQN TYLSGETKSV GAVFIEFATQ SDAQAAYQSL
AHHQALHMTP RYIGVHPSEV VWKSLTISWW QRVIRRFAVV GFISALIVFW AIPVAVVGAI
SNVTYLESFS WLAWLKEVPT WIMGVISGLL PSVALSILMS LVPVIMRLCA KLSGEPTLAR
VELFTQNAYF AFQVVQVFLV VTVAASASSV VYQIIHEPTG ILQLLANKLP TSANFYISYF
IVQGLTVASG VISQVVGFFV FKILYKLLAS TPRKMYAKWT SLSAISWGST LPVFTNIAVI
GITYSCIQPL VLGFACIGMG LFYLAYRYNV LFVTDTQIDT KGLIYPRALQ QLLVGVYLSE
LCLIGLFAIG TAIGPLVLMI VFLIFTVLFH VSLNKAMGPL LDTLPKSLEA YEEELRSELE
AGVSGVSNEK NGEKSGPELT PEPVGRGNLL TRFLKPHIYS DYATLRALVP SAGIDPDNLY
DERTAKNAYY PPAVISESPL LWIPRDEAGI SKQEVLHTSK VIPITDEGCT INEKNKLVWD
TESARPPLWQ PKVFY
//
