ID A0A2S7PBP1_9HELO Unreviewed; 856 AA.
AC A0A2S7PBP1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=DUF221 domain-containing protein {ECO:0000313|EMBL:PQE11705.1};
GN ORFNames=CJF32_00004854 {ECO:0000313|EMBL:PQE11705.1};
OS Rutstroemia sp. NJR-2017a WRK4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Rutstroemiaceae; Rutstroemia.
OX NCBI_TaxID=2070412 {ECO:0000313|EMBL:PQE11705.1, ECO:0000313|Proteomes:UP000238813};
RN [1] {ECO:0000313|EMBL:PQE11705.1, ECO:0000313|Proteomes:UP000238813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJR-2017a WRK4 {ECO:0000313|EMBL:PQE11705.1,
RC ECO:0000313|Proteomes:UP000238813};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PQE11705.1}.
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DR EMBL; NJPR01000123; PQE11705.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S7PBP1; -.
DR InParanoid; A0A2S7PBP1; -.
DR OrthoDB; 366603at2759; -.
DR Proteomes; UP000238813; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000238813};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 29..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 534..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 632..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 694..714
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 720..740
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..204
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 225..427
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 438..713
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 300..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 818..838
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..835
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 96674 MW; AD8B13B48531FF51 CRC64;
MASLMSAFIM AEKDCKSYDP TVPHGDSDII VQLVLSLSLG ISAFFGFCVL RPKWKSLYAA
RKRHVDAAAN LPELPDSFFG WMPALYRVTE EQVLASAGLD AYVFLSFFKM SMKLFAIMFV
MAAAILAPIN AHFYYVTNPF SKDPKHPPGP DYSLVDGWNG GWNEAAILKG GKDSDAPLPD
TSYLWSYLVF TYVFTGLAIF FMTRQTHRII QVRQDYLGSQ YTITDRTIKL SGIPKELRSE
EKITEILERL EIGKVESVTL CRDWKKLDGL MDKRAQVVRR LEEAWTVHLG RQRNSSQGLL
QNVLPTQSAT EQELEEDSET REDANLLGNS HVMPFEQPRP TTKIWYGFLG FQSRKVDAID
HYEEQLRRLD DMIVDARKKE YKPTALAFVT MDSIPACQMA VQALLDPTPG QLVARPSPAP
MDIVWTNTYL SRSSRMIRSW SITIFILLLT IIWLVPVAAL AGLVSLCSIR QVWPELANIL
EDHDVLKALI QTGLPTLVFS LLNLAVPFLY DYLANMQGSI SQGEVELSVI SKNFYFTFFN
VFVVFTVFGT ASSFWPALQE TLKDTTKIAY SLATSIGKLS AFYTNFILLQ SVGLLPFRLL
EFGSVSLYPI TLMGAKTPRD YAELVQPPIF KYGFYLPSAL LIYILCIVYS IQPAGYLVLF
FGVAYFALGY YTYKYQLLYA MDHPQHATGG AWPMIVYRLL IGLGFFQFTM AGVIALQKAF
TPAVLVLPLI PFTVWYSYYF HRTLNPLMRF IALRSIRRNT DPDINIAGED IGIATPPGRY
RRGSTVDEAR ERGMKFVNPS LVVPLEKIWI NKDEEPEAEI NGSTPHLEHL DREESAASSI
SLGDTHIWRD SGDNNV
//
