ID A0A2S7QL43_9HELO Unreviewed; 371 AA.
AC A0A2S7QL43;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=CJF32_00000235 {ECO:0000313|EMBL:PQE27255.1};
OS Rutstroemia sp. NJR-2017a WRK4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Rutstroemiaceae; Rutstroemia.
OX NCBI_TaxID=2070412 {ECO:0000313|EMBL:PQE27255.1, ECO:0000313|Proteomes:UP000238813};
RN [1] {ECO:0000313|EMBL:PQE27255.1, ECO:0000313|Proteomes:UP000238813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJR-2017a WRK4 {ECO:0000313|EMBL:PQE27255.1,
RC ECO:0000313|Proteomes:UP000238813};
RA Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004406}.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PQE27255.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NJPR01000073; PQE27255.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S7QL43; -.
DR STRING; 2070412.A0A2S7QL43; -.
DR InParanoid; A0A2S7QL43; -.
DR OrthoDB; 1133at2759; -.
DR Proteomes; UP000238813; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000238813}.
FT DOMAIN 13..284
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 371 AA; 40630 MW; A5B22050CCDD84F1 CRC64;
MAQTQKPSLG KVLVIGGCGF LGHHIVSLLH DAYTCQISVL DLRTTRNRHS SSSISYHDGD
ITSSSALIAI FNEIKPDVVI HTASPVAING TNDLFYKVNV DGTKCVIEAC QKTGVKALVY
TSSASVISDN VSDLVNADER WPVIPPSKQE EYYSTTKAEA ESLVLAANRA PTCPTLLTAA
IRPSGIFGPG DVQLIPSLLN AYYTSKDGFQ LGDNTNLFDF TYVLNVAHAH LLCARALLST
SSTSTIPLDH ERVDGEAFLV TNCSPVPFWD FVREVWKAAG STKGTEHVWV IGKEFGLGLA
GVVEWVGWAI GRKMKLTKTQ VRFSSMTRYY DVGKAKRRLG YKPLVQLSDG IKISVEWFEE
QRKKEAEKKG L
//
