ID   A0A2S7R139_9HELO        Unreviewed;       945 AA.
AC   A0A2S7R139;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   28-JUN-2023, entry version 17.
DE   SubName: Full=Putative enzyme activator VAC14 protein {ECO:0000313|EMBL:PQE32464.1};
GN   ORFNames=CJF32_00001220 {ECO:0000313|EMBL:PQE32464.1};
OS   Rutstroemia sp. NJR-2017a WRK4.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Rutstroemiaceae; Rutstroemia.
OX   NCBI_TaxID=2070412 {ECO:0000313|EMBL:PQE32464.1, ECO:0000313|Proteomes:UP000238813};
RN   [1] {ECO:0000313|EMBL:PQE32464.1, ECO:0000313|Proteomes:UP000238813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJR-2017a WRK4 {ECO:0000313|EMBL:PQE32464.1,
RC   ECO:0000313|Proteomes:UP000238813};
RA   Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the VAC14 family.
CC       {ECO:0000256|ARBA:ARBA00010225}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PQE32464.1}.
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DR   EMBL; NJPR01000025; PQE32464.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S7R139; -.
DR   STRING; 2070412.A0A2S7R139; -.
DR   InParanoid; A0A2S7R139; -.
DR   OrthoDB; 5481081at2759; -.
DR   Proteomes; UP000238813; Unassembled WGS sequence.
DR   GO; GO:0070772; C:PAS complex; IEA:InterPro.
DR   GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR026825; Vac14.
DR   InterPro; IPR021841; VAC14_Fig4p-bd.
DR   PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR   PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF12755; Vac14_Fab1_bd; 1.
DR   Pfam; PF11916; Vac14_Fig4_bd; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000238813};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          86..121
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   DOMAIN          606..775
FT                   /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT                   /evidence="ECO:0000259|Pfam:PF11916"
FT   REGION          298..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..507
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          812..843
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          896..945
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..317
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..341
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        438..455
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        812..835
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   945 AA;  105001 MW;  8F3A348030271D19 CRC64;
     MDQGIQRALN DKLYDKRKVG ALDLERVIRD LAAAKEFDRI KKIIQQLCND YAYAVHQPHA
     RNGGLIGLAA AAIALGPDLA RYLDEIVPPV LACFTDQDAR VRYYACESMY NIAKVAKGEV
     LPYFNHIFDA LCKASQIVEP PKSAFELMAE QLGADSELSV KNGAELLDRL IKDIVSESAA
     TYVSILHTSD DSMSDSKEET LEDSEDLPTA FSLARFIPLL KERIYVINPF TRTFLVGWIT
     LLDSIPDLEL VSFLPEFLGG LFKFLSDPNR DVHVATQGAL ERFLNEIKRI SRIKKGIEES
     RKSRSDTKRK RSGSMDSDGS EAPDGGADDD SVMDPDDKDI SSDDDWVPGQ DVHVNHKEIL
     EILTANLDAP LEEDSLLESL RWIVEFLDIC PEEVLPFAPK ILAHLLPAMA SGVETIRQAA
     ARVNTSLMDY VVSLSDEGAT SEVPSSIPSR FPSMKETNPT ERRDSSATNR GSLSGSRELD
     KRETDVQTPP PPASKAQTPT PPNQPQVDLD YAAAVSSLTL LFLNDHEATR VAALTWLLML
     HRKAPKKVLA FNDGTFPALL KTLSDPAEAV VTKDLQLLSQ ISRNSEDDYF TSFMVNLLQL
     FSTDRKLLET RGNLIIRQLT LADCIEKEED VEFASIMVQN LNNNLITAPE LAELRKRLRN
     IENKVLKAFD YRDWSLLTSW CYNAVATFSL CLLGQAYEQA YNLLQIFAEL EMTVNMLIQI
     DKLVQLLESP VFTYLRLQLL EPEKYPHLYK CLYGLLMLLP QSSAFAALKN RLNSVSAIGY
     LHIAPRAYVS SSRNNSVADA FSTFALHQRQ KSGTETHASS PSFSVQATAG PSNYDRTSRL
     KGGREESGIR WGELLEKFRS VQEKARRARR PGGDMDDGLG GFETRMEAVD GRGFKDLTRL
     PGPPPQPIKE PTVSMPAGPQ HTKSRSSLGK FGRLGGAVAG GRPRK
//