ID A0A2S7U541_9BACT Unreviewed; 1517 AA.
AC A0A2S7U541;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=VWFA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BSZ32_13725 {ECO:0000313|EMBL:PQJ29442.1};
OS Rubritalea profundi.
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Rubritaleaceae; Rubritalea.
OX NCBI_TaxID=1658618 {ECO:0000313|EMBL:PQJ29442.1, ECO:0000313|Proteomes:UP000239907};
RN [1] {ECO:0000313|EMBL:PQJ29442.1, ECO:0000313|Proteomes:UP000239907}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAORIC-165 {ECO:0000313|EMBL:PQJ29442.1,
RC ECO:0000313|Proteomes:UP000239907};
RA Song J., Yoshizawa S., Kogure K.;
RT "Study of bacterial adaptation to deep sea.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PQJ29442.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MQWA01000001; PQJ29442.1; -; Genomic_DNA.
DR OrthoDB; 198275at2; -.
DR Proteomes; UP000239907; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.880; -; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR024163; Aerotolerance_reg_N.
DR InterPro; IPR011635; CARDB.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR011933; Double_TM_dom.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR NCBIfam; TIGR02226; two_anch; 1.
DR PANTHER; PTHR37947; BLL2462 PROTEIN; 1.
DR PANTHER; PTHR37947:SF1; BLL2462 PROTEIN; 1.
DR Pfam; PF07584; BatA; 1.
DR Pfam; PF07705; CARDB; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 2.
DR SUPFAM; SSF53300; vWA-like; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000239907};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 56..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 743..763
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 775..793
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..76
FT /note="Aerotolerance regulator N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07584"
FT DOMAIN 94..199
FT /note="VWFA"
FT /evidence="ECO:0000259|Pfam:PF13519"
FT DOMAIN 242..317
FT /note="CARDB"
FT /evidence="ECO:0000259|Pfam:PF07705"
SQ SEQUENCE 1517 AA; 166829 MW; DBF4E32161ABE945 CRC64;
MNFLNPLLLL GALGISLPIL AHLLNQQKVK KTEWAAMQFL NRNVRVRSSQ IKLRDLLLLL
LRCFALLLLV LAFARPAWEN TAPSWIPGEP RAGVVIGIDA SFSMDHGGEG TSRFDRAIEQ
VETISEQIQA GDPVSVILLG GEDKVLINNM AFNRERFTDI IQKAKPVPAL LDLDRVPKRL
KELVDDMEAP QKEVYFISDV QQRDWRRTSA SFQQALGDLR NDASVFLIPV PGDPANLAVT
ELDLVSGMLR KGTTARYQAT VKNCGSSPVA NVEIQCRVEG VQIDSKIIPS IAAGASETVS
LFVPFYNAGA TRITAEISGD LLPTDNVRRV VAVVRDRVSV LCVDGSNGDA GRLIVSALLA
RNDGAQDEDY IVRAVPWLSL PTEPLEEVDV IILADVPEIT PQQVEQLSRF VRQGNGLVWF
AGKNVKAAVW NERTASGPNP LLPAKLGSPV DANTKLGAGQ PLDPSMPDHS VCLPLLSLPE
DLFSETRFLT RLSVEPTASS FPILSLAGSG APILLEHSLG RGHVFQFTTS ADTSWNNMAL
TPVFPMLMQQ IVTYLSGREF EQPRVVGDSL SLTYVEQPDA SNAVFDTPSG ESITVPVREH
RNQFVAMLEG ATEAGFYETK VSVQAAGVPV AVNVDPSEST VTSLAAADLN ANLEGLDITI
INSGAELTSA IKSSRTGRSS WRQFMLAGIV LLLLESLLAD RYAAANKRKI SKQLCLNPFP
KYKMSEPIPI INQVEQFFLA RPLPTGTLVV IFAAIVLLSI YLYRRPWGLP MWLRASLVIV
RVLVLALIVL TLLEPTRVVT ETHTRVRSLP VLLDVSESMS MKDQRKSSED LVDAATALGM
VSLEEKAEAD NAVMALDTKQ RLAISSASRL DLGAAILSQS GRPVFESLSE SLDLSYHAFG
ETSRLISDGK VVTSKDLAGL KADGSSTSIA ASLEAAANAG GIPPAGIILL SDGIDNTSSQ
RSEAVLQDLG ARGIPVYTVP LGLPNPDDVA IRNIVMQEVA FSGDSVPVRV HLESQGYEQR
TARLSVLLND RRVSSRVVRF EGGLQFEEVD FSVDIYEKGA AQIDVIIEPF EDEVSTVNNR
VTRSIRVVNE KVNVLYIEGN ARWEFRYLRA ILKRDPRIDT TFIASNAGPE VARNSPEHIE
RFPSNREEAF KYDLVILGDV DASFFSDEEF GLLEELIRDR GASLLMLCGP MHSPGSYAGT
PVQTMLPVRF DSEAGWDKVA ESVYPVLTPE GRNSLVMTLE NDMDLNDRIW SRMAPMDQLP
PLLSAKPAAT VLAMLSDSTS RDQGYPLVAW QRYGSGKCMT IASDRLWRLR YKTGDKYHWR
VWSQCIQFMT LSRLMGEHKR IRLETDRSVY PVDGQCRVYA HVLDKEYEPI SQPAFEVYVS
NLAGGQAKQL ISLRPDSTQP GLYEGYFTPS EAGRYRLEAN ENDKQISSTT EFQVSDIQQE
LLDTGMRSDH LQRIADLTGG SKLGVRELNK LTDLINGDPV TITLRSERPL WDNMLVVLLL
VGLLGAEWIL RRKNDLP
//
