ID A0A2S7UWM3_9GAMM Unreviewed; 447 AA.
AC A0A2S7UWM3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Zinc metalloprotease {ECO:0000256|RuleBase:RU362031};
DE EC=3.4.24.- {ECO:0000256|RuleBase:RU362031};
GN ORFNames=BTO11_08315 {ECO:0000313|EMBL:PQJ53670.1};
OS Psychrosphaera saromensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Pseudoalteromonadaceae; Psychrosphaera.
OX NCBI_TaxID=716813 {ECO:0000313|EMBL:PQJ53670.1, ECO:0000313|Proteomes:UP000239007};
RN [1] {ECO:0000313|EMBL:PQJ53670.1, ECO:0000313|Proteomes:UP000239007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA4-48 {ECO:0000313|EMBL:PQJ53670.1,
RC ECO:0000313|Proteomes:UP000239007};
RA Yoshizawa S., Kogure K.;
RT "Diversity of luminous bacteria.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU362031};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peptidase M50B family.
CC {ECO:0000256|ARBA:ARBA00007931, ECO:0000256|RuleBase:RU362031}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PQJ53670.1}.
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DR EMBL; MSCH01000003; PQJ53670.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S7UWM3; -.
DR OrthoDB; 9782003at2; -.
DR Proteomes; UP000239007; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00989; PDZ_metalloprotease; 2.
DR CDD; cd06163; S2P-M50_PDZ_RseP-like; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004387; Pept_M50_Zn.
DR InterPro; IPR008915; Peptidase_M50.
DR NCBIfam; TIGR00054; RIP metalloprotease RseP; 1.
DR PANTHER; PTHR42837:SF2; MEMBRANE METALLOPROTEASE ARASP2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR42837; REGULATOR OF SIGMA-E PROTEASE RSEP; 1.
DR Pfam; PF02163; Peptidase_M50; 1.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362031};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362031};
KW Metal-binding {ECO:0000256|RuleBase:RU362031};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU362031};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:PQJ53670.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000239007};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362031};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362031};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU362031}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 98..123
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT TRANSMEM 423..441
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362031"
FT DOMAIN 208..287
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
SQ SEQUENCE 447 AA; 48550 MW; 670F99CF075332FC CRC64;
MTGFIWNLFS FILALGILVF IHEYGHYWVA KKNGIKVLKF AVGFGKPIYT WRNKSGTDFV
VGIIPLGGYV RMLDERIDEV LPQDKLTAFN NKTVLERIAV IAAGPMANFI FAIVVLFAVF
MMGGKAVKPV VGKVDESSIA ANSGVMANDV ILSIDGQETS SWESANFALI EQVGKESFDL
IVERNNDQTN LLVKANGWGI EDGQVLKGLG IQPYRPTPLL TLALIAEGSP AQVGGLLVHD
KLLSINGIAL SGWQEATEII ASNAEKAMTV IIDRNGQNLT LSITPENRPT KDGFSQGYLG
VAPDVENWPK GYVFDVQYGI FPALKKSVEQ TWLFISLTFQ MVGKLVTGDI GLNNLSGPIS
IAQGAGQSAE SGLVNFLKFL ALISINLGVV NLLPLPVLDG GHLMYFIIEL IRGKPVSERV
QEMGFKIGAF ILMMIMGIAI INDFGRL
//
