ID   A0A2S7WMS3_9FLAO        Unreviewed;       702 AA.
AC   A0A2S7WMS3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Aminopeptidase {ECO:0000313|EMBL:PQJ78561.1};
GN   ORFNames=BTO18_04880 {ECO:0000313|EMBL:PQJ78561.1};
OS   Polaribacter porphyrae.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=1137780 {ECO:0000313|EMBL:PQJ78561.1, ECO:0000313|Proteomes:UP000238882};
RN   [1] {ECO:0000313|EMBL:PQJ78561.1, ECO:0000313|Proteomes:UP000238882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 108759 {ECO:0000313|EMBL:PQJ78561.1,
RC   ECO:0000313|Proteomes:UP000238882};
RA   Kumagai Y., Yoshizawa S., Kogure K., Iwasaki W.;
RT   "Trade-off between light-utilization and light-protection in marine
RT   flavobacteria.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PQJ78561.1}.
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DR   EMBL; MSCN01000001; PQJ78561.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S7WMS3; -.
DR   OrthoDB; 9814383at2; -.
DR   Proteomes; UP000238882; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09604; M1_APN_like; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR11533:SF303; AMINOPEPTIDASE N; 1.
DR   PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:PQJ78561.1};
KW   Hydrolase {ECO:0000313|EMBL:PQJ78561.1};
KW   Protease {ECO:0000313|EMBL:PQJ78561.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000238882};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..702
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015466174"
FT   DOMAIN          390..565
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
SQ   SEQUENCE   702 AA;  81456 MW;  E5895AD71AD4AEC6 CRC64;
     MKKISFILFS FAFIGTFYAQ KAKQGHTNTN KFRQLKQELA TPNSIRTASG APGKDYWQQK
     VDYVMDITLD DDKRRISGKE TITYKNNSPD YLPYLWVQLD QNMRAADSKT PDISSGKIRK
     KLPKRWYDRS FPDKPFDGGF NIMSVTNTDG SKLSHTINQT MMRINLPEPL ASGETFKFNI
     SWWYNINNHR TQGGRSGYEH FEENGNNNYV IAQFYPRMCV YDNVEGWQND QFWGRSEFAL
     EFGDFDVNIT VPEDHMLGAT GVLQNRSEVF SRKELKRYAT AKKTFDKPVI IRTQKEAEKI
     EKSKAKGTKT WKFKAKNVRD YAFATSRKFI FDAMAVNING KTVMAESLYS KEANPLYGDH
     STRAVAQTLK TYSRYTFDYP YHKAISVDGQ MGMEYPQICF NPGRPNPDGT YSDRTKYRMI
     KVTIHEVGHN FFPMIVNSDE RQWTWMDEGL NSYMEMLAEL DYDPNFPITR GYPKNIVRYM
     SGNQDRIAPI MSKGDNVYSF GSNAYGKPAT GLWMLRETIM GRELFDHAFK TYSQRWKFKH
     PTPADFFRTM EDASGIDLDW FWRGWFYTTD VTDIGIKGVK KFSAKEGEKS VEFIEDTSEG
     LGFASKQDKY HYEITYNKPG GLVMPIIVEF TYKDGTKEKK MYPAEIWRYN DNEVTKVFSS
     NKQVESIMID PDLETADVDT SNNSFPKEKA NKFDKFKKKM KG
//