ID A0A2S8B8K5_9SPHN Unreviewed; 348 AA.
AC A0A2S8B8K5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=CVO77_09950 {ECO:0000313|EMBL:PQM28742.1};
OS Sphingopyxis lindanitolerans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=2054227 {ECO:0000313|EMBL:PQM28742.1, ECO:0000313|Proteomes:UP000238954};
RN [1] {ECO:0000313|Proteomes:UP000238954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WS5A3p {ECO:0000313|Proteomes:UP000238954};
RA Kaminski M.A.;
RT "The complete genome sequence of Sphingopyxis pomeranensis sp. nov. strain
RT WS5A3p.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PQM28742.1}.
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DR EMBL; PHFW01000002; PQM28742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S8B8K5; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000238954; Chromosome.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000238954}.
FT DOMAIN 13..335
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 348 AA; 37725 MW; 8D8262F0AA36A120 CRC64;
MTDDVIIAKE GRIGRISLNR PKAIHALNLA MCEAMIAALV QWQDDDAVEA VIIDHSEGRG
FCAGGDIRML AESGAKDGKE ARAFFHTEYR LNHLLFTYAK PVAAFMDGIT MGGGVGISQP
AKYRVATDHT RFAMPETGIG LFPDVGGGWY LPRLEGRVGA FLALTGARLD GAECLALGLA
THYLPSERLA EAKARIAAHP DRIGGILGEL SVTAPPAAIT SRIDKINRLF ASDTYEDILA
ALEADGGEWA GKELDALRTK SPQTCKVALR QLKEGGAMTD FAEQMRQEYA IGARVVQMHD
FLEGVRALII DKDNSPQWDP PTPEAVTDAW IDAIFVPLPD DEQWTPLT
//
