ID   A0A2S8SRU9_9BACT        Unreviewed;       840 AA.
AC   A0A2S8SRU9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Adenylate cyclase, class 3 {ECO:0000313|EMBL:PQV63534.1};
GN   ORFNames=B1R32_11195 {ECO:0000313|EMBL:PQV63534.1};
OS   Abditibacterium utsteinense.
OC   Bacteria; Abditibacteriota; Abditibacteriia; Abditibacteriales;
OC   Abditibacteriaceae; Abditibacterium.
OX   NCBI_TaxID=1960156 {ECO:0000313|EMBL:PQV63534.1, ECO:0000313|Proteomes:UP000237684};
RN   [1] {ECO:0000313|EMBL:PQV63534.1, ECO:0000313|Proteomes:UP000237684}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 29911 {ECO:0000313|EMBL:PQV63534.1,
RC   ECO:0000313|Proteomes:UP000237684};
RX   PubMed=29475572;
RA   Tahon G., Tytgat B., Lebbe L., Carlier A., Willems A.;
RT   "Abditibacterium utsteinense sp. nov., the first cultivated member of
RT   candidate phylum FBP, isolated from ice-free Antarctic soil samples.";
RL   Syst. Appl. Microbiol. 0:0-0(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PQV63534.1}.
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DR   EMBL; NIGF01000011; PQV63534.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S8SRU9; -.
DR   InParanoid; A0A2S8SRU9; -.
DR   OrthoDB; 1522078at2; -.
DR   Proteomes; UP000237684; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000237684};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        447..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        492..515
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        521..544
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          587..715
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          799..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        799..827
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   840 AA;  93390 MW;  D05E77C546CEB4C1 CRC64;
     MASNKTQVGP LGFNELSARP ENDFSRLVVP EVARQFKRGQ SGAKRPNLMN RILSSCLRAA
     RSKSLWGETS VRSLAAVALI CGLSCALMVP QILNFATRDQ IERQVCNGLP LWSALERGEY
     TLLDRRFADR GARKPRSLDS IVIVGIDEAS QKMLKQWPFK RGLHAQLIEK LHTAGARVIG
     LDIGFDAYDP DSERDPRTGQ MKFSRDHLAL ESALKKAGNV VLVSHIDTQF KKSADSATQS
     NRFAVGTPID EFDALTPDVA ISYVPRDLDG SVRRYPFSYL TPPETEPLGS FAPLCVAVFQ
     NLIHGEDLTR YQSRLRAGKW FDAHGLARNL PLSHGVFPGE SKPADRMQTW LTPLLFWGPP
     GTFATYSYSD VLKVWNEPEL KKRFQDRIVF VGATDQLLKD TFSVPAFNGE SGDQITPEMP
     GVEIHATMAA MLLDGAYLKT QTTNSTLWTL LALTLSASVW TTLVCRWTSL AARRAQAWWA
     SRKLPGRVHS PLWIGLCALL GPLPIVAFWL GASWAFSHFN LWIVVIYPAL GAALASVATL
     LLLFGAESSD RRKVLTQMSR LVAPDVMDEI LAHPEEDYPR PRRVHATVLF TDLEGFTSYS
     EAREPEEVVT ALNEYFKRMQ PIVHAYGGSV DKYIGDSVMA FFGAPVPRPD HAAQALRCAI
     AMQDECARFR QETGVPFWMR VGVHTGDLIV GGVGSDEQNN YTAIGDTVNL ASRLEASNKS
     FGSRIICSAQ THSRAPDVAR VERSQTPIRG KSGDIEILIV RGPLDEPPRD ALWGHGDLEI
     DWKTHLQIDR RIEPDRRLDV DRRRPADRRS GEKRGSARDR RSAAKTENET ENALQKSIGE
//