ID A0A2S9PRQ1_9ACTN Unreviewed; 349 AA.
AC A0A2S9PRQ1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:PRH77017.1};
GN ORFNames=C6N75_22515 {ECO:0000313|EMBL:PRH77017.1};
OS Streptomyces solincola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2100817 {ECO:0000313|EMBL:PRH77017.1, ECO:0000313|Proteomes:UP000239322};
RN [1] {ECO:0000313|EMBL:PRH77017.1, ECO:0000313|Proteomes:UP000239322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST5x {ECO:0000313|EMBL:PRH77017.1,
RC ECO:0000313|Proteomes:UP000239322};
RA Tan G.Y.A., Lee Z.Y.;
RT "Novel Streptomyces sp. from soil.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRH77017.1}.
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DR EMBL; PVLV01000387; PRH77017.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S9PRQ1; -.
DR OrthoDB; 3324394at2; -.
DR Proteomes; UP000239322; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06292; PBP1_AglR_RafR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000239322};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 3..58
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 349 AA; 36579 MW; D7380CB9C1E175F8 CRC64;
MTARLADIAA QAGVSEATVS RVLNGKPGVA AATRQSVLAA LDVLGYERPV RLRQRSAGLV
GLITPELDNP IFPALAQVIG QGLTRQGYTP VLATQTPGGS TEDELTEMLV ERGVSGIIFV
SGLHADTTAD TQRYDQLRGK GVPYVLINGY SPKVEATFVS PDDRAAMQLA VTHLASLGHT
RIGLAVGPKR FVPVLRKIEG FALGMQAKLG LSPEQCEELV QHSLYTLEGG QAAASALIER
GCTAVVCASD MMALGAIRAA RQRGLTVPGD VSVVGFDDSP LIAFTDPPLT TIRQPVQAMG
QAAVRALLEE IGGTPAPPSE FVFMPELVVR GSTAAGPGGR RPRLSQGRE
//
