ID A0A2S9PW38_9ACTN Unreviewed; 409 AA.
AC A0A2S9PW38;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Dolichol-phosphate mannosyltransferase {ECO:0000313|EMBL:PRH78573.1};
GN ORFNames=C6N75_14220 {ECO:0000313|EMBL:PRH78573.1};
OS Streptomyces solincola.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2100817 {ECO:0000313|EMBL:PRH78573.1, ECO:0000313|Proteomes:UP000239322};
RN [1] {ECO:0000313|EMBL:PRH78573.1, ECO:0000313|Proteomes:UP000239322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST5x {ECO:0000313|EMBL:PRH78573.1,
RC ECO:0000313|Proteomes:UP000239322};
RA Tan G.Y.A., Lee Z.Y.;
RT "Novel Streptomyces sp. from soil.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family.
CC {ECO:0000256|ARBA:ARBA00006739}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRH78573.1}.
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DR EMBL; PVLV01000196; PRH78573.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2S9PW38; -.
DR OrthoDB; 9810303at2; -.
DR Proteomes; UP000239322; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR InterPro; IPR039528; DPM1-like.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR007267; GtrA_DPMS_TM.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43398:SF2; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE; 1.
DR PANTHER; PTHR43398; DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR Pfam; PF04138; GtrA; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000313|EMBL:PRH78573.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000239322};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PRH78573.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 257..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..187
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
FT DOMAIN 260..374
FT /note="GtrA/DPMS transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04138"
FT REGION 382..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 43983 MW; 43828DCBDDB2B655 CRC64;
MTGERPHPAG PAEPAAVTLV IPTFNESANV RELLRRIAES VPARLPCEVL FVDDSTDDTP
AVIADAARDC PFPVTALHRE SPDGGLGGAV VAGLAAATAD WVVVMDGDLQ HPPHLVPELV
ATGERTGAEL VVASRYLPGG SRAGLAGGYR VAVSRAATWL AKGLFPRALK SVSDPMSGFF
AIRRSAVADA VTGDELKPLG YKILLELAVR CRPETVAEAP FVFQDRYAGE SKSTAREGMR
FLRHLVELRT AAPLARMVAF GLIGLTGFVP NLAALWALTA AGLHYLPAEV AANQFGVAWN
FLLIEVLLFR DRRRHRHFAD RAGRFALLAN ADLVVRIPLI ALFVGQLHLT VLPATALALL
TTFVLRFAGT EALVYLPRRE RRGRPRGGAD RTARRPRTAG EARTERTPG
//
