ID   A0A2S9QKN3_9MICO        Unreviewed;       361 AA.
AC   A0A2S9QKN3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=S-(Hydroxymethyl)mycothiol dehydrogenase {ECO:0000313|EMBL:PRI10150.1};
GN   ORFNames=B4915_13565 {ECO:0000313|EMBL:PRI10150.1};
OS   Leucobacter massiliensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Leucobacter.
OX   NCBI_TaxID=1686285 {ECO:0000313|EMBL:PRI10150.1, ECO:0000313|Proteomes:UP000238650};
RN   [1] {ECO:0000313|EMBL:PRI10150.1, ECO:0000313|Proteomes:UP000238650}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=122RC15 {ECO:0000313|EMBL:PRI10150.1,
RC   ECO:0000313|Proteomes:UP000238650};
RX   PubMed=29204283;
RA   Leangapichart T., Gautret P., Nguyen T.T., Armstrong N., Rolain J.M.;
RT   "Genome sequence of 'Leucobacter massiliensis' sp. nov. isolated from human
RT   pharynx after travel to the 2014 Hajj.";
RL   New Microbes New Infect 21:42-48(2017).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRI10150.1}.
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DR   EMBL; MWZD01000023; PRI10150.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S9QKN3; -.
DR   OrthoDB; 334894at2; -.
DR   Proteomes; UP000238650; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08279; Zn_ADH_class_III; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR017816; MycoS_dep_FDH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   NCBIfam; TIGR03451; mycoS_dep_FDH; 1.
DR   PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR43350:SF19; RIBULOSE-5-PHOSPHATE REDUCTASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000238650}.
FT   DOMAIN          17..361
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   361 AA;  37843 MW;  AB342ADAE12F5B4D CRC64;
     MVYRVQGVVV REKNAPAEIA TILVPEPGPG EVVVDVLTCG VCHTDYHYQQ GGIGDEFPYL
     LGHESTARVA VVGEGVTEVA VGDRVILNWR AVCGQCRACR KGQPQYCFAT HNATQKMTLE
     DGTPLSAALG IGSFAEKTLV AAGQCTKIDE ESDAAAVGLL GCGIMAGIGA AINTGEVRRG
     ESVAVIGCGG VGTAAIAGAQ LAGATTIVAV DIDDAKLEQA KRFGATHTVN SRSEDAVEAI
     RALTGGFGAD VVIDAVGRPE TYRQAFYARD LAGRVVLVGV PTPEMQLELP LLDVFGRGGS
     LKSSWYGDCL PSRDFQMLID QYRLGRLDLE GFVTERIGLG DVEEAFGKMA GGNILRSVVV
     L
//