ID   A0A2S9Z1X9_9CORY        Unreviewed;       474 AA.
AC   A0A2S9Z1X9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=C1Y63_06490 {ECO:0000313|EMBL:PRQ11352.1};
OS   Corynebacterium sp. 13CS0277.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=2071994 {ECO:0000313|EMBL:PRQ11352.1, ECO:0000313|Proteomes:UP000238368};
RN   [1] {ECO:0000313|EMBL:PRQ11352.1, ECO:0000313|Proteomes:UP000238368}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13CS0277 {ECO:0000313|EMBL:PRQ11352.1,
RC   ECO:0000313|Proteomes:UP000238368};
RA   Busch A., Hotzel H., Tomaso H., Thomas P., Nguyen T.;
RT   "Corynebacterium vierzehnheiligense, a novel Corynebacterium species
RT   recovered from Common kestrel (Falco tinnunculus).";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRQ11352.1}.
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DR   EMBL; PPDL01000012; PRQ11352.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2S9Z1X9; -.
DR   OrthoDB; 9779574at2; -.
DR   Proteomes; UP000238368; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01430; aden_deam; 1.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000238368}.
FT   DOMAIN          63..405
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   474 AA;  50605 MW;  35BF13C399670720 CRC64;
     MSTTDSPQHA TDDHTHADHG HAHAHHGHTH ADHVETREQE VAHVTSHLTP GAPLDEAIVH
     ALPKVVLHDH LDGGLRPATI VELAAACGYE GLPTTDPEEL GRWFVEAANS GSLPSYLECF
     DHTTAVMQTA DALERVAREA VADLAADNVV YAELRFAPEQ HQAQGMSLQE VMDAVIRGLA
     AGEEAAAAAG RPIVARLIVC GMRHADRTKE IAQLTIDNYG ADSPGRGYVV AFDIAGAEDG
     FPATRHKEAF DLLRAAYVPF TVHAGEAAGI DSLAGALEVG AARLGHGARL YEDFSASLDG
     IDPGRLSSYV RDRRLALELC PTSNTQTGVV DDMADHPLPL LHQLGFAVTV NTDNRLLGDT
     TMTGEMMVLV RYFDYTLGSL YTLTLNAISQ AFISELQREE ISATLIEPTY ARIGAALQGD
     LSDDTQDTPT GPELAQQMQL SEEELAGIDP AILEELGISL DDLGITGGTT PENS
//