ID A0A2T0B2P2_9CLOT Unreviewed; 572 AA.
AC A0A2T0B2P2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Coproporphyrinogen III oxidase {ECO:0000313|EMBL:PRR78164.1};
GN ORFNames=CLLI_19280 {ECO:0000313|EMBL:PRR78164.1};
OS Clostridium liquoris.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1289519 {ECO:0000313|EMBL:PRR78164.1, ECO:0000313|Proteomes:UP000239706};
RN [1] {ECO:0000313|EMBL:PRR78164.1, ECO:0000313|Proteomes:UP000239706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100320 {ECO:0000313|EMBL:PRR78164.1,
RC ECO:0000313|Proteomes:UP000239706};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Clostridium liquoris DSM 100320.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRR78164.1}.
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DR EMBL; PVXO01000051; PRR78164.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0B2P2; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000239706; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR025288; DUF4080.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF18; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13311; DUF4080; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000239706}.
FT DOMAIN 1..133
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 176..409
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 572 AA; 67914 MW; B546340582FAAA34 CRC64;
MKVILTAVNS KFIHSNLAVR YLKSYTKDLN YECIIKEFSI NDRVERIVQE LIYEKPDIIA
FSCYIWNIEY VDRISRLIKL INKDIVILFG GPEVSYDGAS YLKDENCDYV IEGEGENTYR
EFIEYMMKSH EGKPLIEDIY NIKGIFYKHN GDIIYTGKRE LMDMNKLVFP YEENEDLSNK
IVYYEASRGC PFNCKYCLSS TTHGVRFLNI ERVKKELRLF IDKKVRLVKF VDRTFNCNEK
FASQIWEFLI EQQTETTFHF EISADILTEE EIELLSKAPK GRFQFEVGVQ TTNNEVLKNI
NRKANFNHIK EKVEELMKIK NINQHLDLIA GLPGEDYGSF INSFDDLYTI HPEEIQLGFL
KLLKGSSMRE EVKKWGMVYS PYPPYEILKT KDISYEELLQ LKRVEEMVDK YYNSGKFNNI
LKYFIHKSSS SYSFYHSLGE FFYHKGYFAR SISSSDYYKV FLEYNEEELG EDNKILNEVV
KFDYLKFNKK KWLPDFLSRE EDKTSERKIK ENLINSNILK NDRSTNSYHI EKFSINIIKF
IDDDKTEKED TFILFGEKNK NLVKDVTMWL NM
//
