ID   A0A2T0B3Z5_9CLOT        Unreviewed;       434 AA.
AC   A0A2T0B3Z5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Vancomycin B-type resistance protein VanW {ECO:0000313|EMBL:PRR78487.1};
GN   Name=vanW_2 {ECO:0000313|EMBL:PRR78487.1};
GN   ORFNames=CLLI_15710 {ECO:0000313|EMBL:PRR78487.1};
OS   Clostridium liquoris.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1289519 {ECO:0000313|EMBL:PRR78487.1, ECO:0000313|Proteomes:UP000239706};
RN   [1] {ECO:0000313|EMBL:PRR78487.1, ECO:0000313|Proteomes:UP000239706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 100320 {ECO:0000313|EMBL:PRR78487.1,
RC   ECO:0000313|Proteomes:UP000239706};
RA   Poehlein A., Daniel R.;
RT   "Genome sequence of Clostridium liquoris DSM 100320.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRR78487.1}.
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DR   EMBL; PVXO01000044; PRR78487.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0B3Z5; -.
DR   OrthoDB; 9797191at2; -.
DR   Proteomes; UP000239706; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR011098; G5_dom.
DR   InterPro; IPR007391; Vancomycin_resist_VanW.
DR   InterPro; IPR022029; YoaR-like_PG-bd.
DR   PANTHER; PTHR35788; EXPORTED PROTEIN-RELATED; 1.
DR   PANTHER; PTHR35788:SF1; EXPORTED PROTEIN-RELATED; 1.
DR   Pfam; PF07501; G5; 1.
DR   Pfam; PF12229; PG_binding_4; 1.
DR   Pfam; PF04294; VanW; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000239706};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          106..220
FT                   /note="YoaR-like putative peptidoglycan binding"
FT                   /evidence="ECO:0000259|Pfam:PF12229"
FT   DOMAIN          404..430
FT                   /note="G5"
FT                   /evidence="ECO:0000259|Pfam:PF07501"
SQ   SEQUENCE   434 AA;  49044 MW;  025653D6E5E6CF17 CRC64;
     MQLETNNSDY SRRQSKVHKR KIHRKRIAII TLTILFIMTV VISGFHAIKV YSTVKKYDNL
     IYPGIFIEGV NVGGKTKKDA LSLLSQKYKE SNKERNIIIK VLDKKYTINF SQLNIEYNYD
     EVINSAFNIH KDEDILKKYK AIKKPKNEEL ELKYKYSSKK IDEMIKNIEN ENNRDAVDAK
     IVNSPSGGFA VKEESYGQAV DKNSIKNAID KNMNIKGKGN VVVNSAIKEV KPHITQKDLG
     TVNSMISSFT TNFSASNDNR ATNINLASDA INGKVVLPGD SFSFNDVVGM RTEEKGYKPA
     KVIVGNEFID DFGGGVCQVS STLYNAIMRA NIPSTERTHH TIASTYVPLG MDATVDFGNI
     DYKFKNTLKY PIYIESVIQN KNLTFNVYSN KSLTSRTYDL VNEVKGNRVN VYKVTYENGK
     EIDRQLVSSD AYDK
//