ID   A0A2T0BNC1_9CLOT        Unreviewed;       719 AA.
AC   A0A2T0BNC1;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   Name=helD_2 {ECO:0000313|EMBL:PRR85379.1};
GN   ORFNames=CLLU_16610 {ECO:0000313|EMBL:PRR85379.1};
OS   Clostridium luticellarii.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1691940 {ECO:0000313|EMBL:PRR85379.1, ECO:0000313|Proteomes:UP000237798};
RN   [1] {ECO:0000313|EMBL:PRR85379.1, ECO:0000313|Proteomes:UP000237798}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 29923 {ECO:0000313|EMBL:PRR85379.1,
RC   ECO:0000313|Proteomes:UP000237798};
RA   Poehlein A., Daniel R.;
RT   "Genome sequence of Clostridium luticellarii DSM 29923.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRR85379.1}.
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DR   EMBL; PVXP01000018; PRR85379.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0BNC1; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000237798; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF17; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000237798}.
FT   DOMAIN          209..566
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   COILED          590..617
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   BINDING         230..237
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   719 AA;  83779 MW;  C09CDA9A7B3F6529 CRC64;
     MYEDDLESEL NREIQLNSER EKLNEVLKQI DAKMMESIGF RKKVVDYILY LRKKNLEQYE
     DDEDRTVEYF NHEVYTKEEQ FRLINKSIRE LTVLKGTPYF GKVSFEDEYG VEEIYIGRFG
     MSSREDYEPV IVDWRSPVCS LFYSGSLGST SYRSPGGTVK ADVLGKRQFI IKKSKLLGMF
     DSNMDVKDEI LQMVLSKNSG QKLKDIVMTI QKEQDALIRQ PREGAVVVNG IAGSGKTTVA
     LHRVAYLLYN YRKLLQGKVL ILGPNSIFMD YISLVLPSLG EEGVTQLTFG EFAESILHLP
     DIMDLKEYME NILRADKQFM DEIIYKNSLE FIADMDKLVS RLEKNCFAAE NVLFYDKIIV
     TKEEMENMLG YYFKDMPLFK RSRRLKGVIY SRIKDERNVR VQSIQKKYRR KIENMTKEEL
     NAQGTNLEYK KRIEIEEVIK EVIRIKKRKL KWLEEPDIVS LYKNFNGDKK LIYDDLAAIL
     YLKMKLDGSR YREKMKHIVI DEAQDYSPLQ FKVIKELTGC RSFTVVGDVN QRIVPSKEVP
     AMMNLNDIFS GLEIKNFLLN KSYRSTNEIT SYANRYLKNS RNISPIRRGT EVVEKKMDNL
     EELVDRILED IEKLKEKGYE STAVICRDLA DTEALGSLLK KKTYIKLISG ENMIYSSGEV
     ILPSYFSKGL EFDAVIMVDS SYQSDENTLK YIVASRALHE LHVYSISSIT REKELRQYE
//