ID A0A2T0FC17_9ASCO Unreviewed; 3729 AA.
AC A0A2T0FC17;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Transcription-associated protein 1 {ECO:0000313|EMBL:PRT52510.1};
GN ORFNames=B9G98_00130 {ECO:0000313|EMBL:PRT52510.1};
OS Wickerhamiella sorbophila.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Trichomonascaceae; Wickerhamiella.
OX NCBI_TaxID=45607 {ECO:0000313|EMBL:PRT52510.1, ECO:0000313|Proteomes:UP000238350};
RN [1] {ECO:0000313|EMBL:PRT52510.1, ECO:0000313|Proteomes:UP000238350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS02 {ECO:0000313|EMBL:PRT52510.1,
RC ECO:0000313|Proteomes:UP000238350};
RA Ahn J.O.;
RT "Genome sequencing of [Candida] sorbophila.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRT52510.1}.
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DR EMBL; NDIQ01000001; PRT52510.1; -; Genomic_DNA.
DR STRING; 45607.A0A2T0FC17; -.
DR OrthoDB; 3666795at2759; -.
DR Proteomes; UP000238350; Unassembled WGS sequence.
DR CDD; cd05163; PIKK_TRRAP; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003152; FATC_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR003151; PIK-rel_kinase_FAT.
DR InterPro; IPR014009; PIK_FAT.
DR InterPro; IPR046807; Tra1_central.
DR InterPro; IPR046805; Tra1_ring.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF1; TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN; 1.
DR Pfam; PF02259; FAT; 1.
DR Pfam; PF02260; FATC; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF20175; Tra1_central; 1.
DR Pfam; PF20206; Tra1_ring; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51189; FAT; 1.
DR PROSITE; PS51190; FATC; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000238350}.
FT DOMAIN 2593..3145
FT /note="FAT"
FT /evidence="ECO:0000259|PROSITE:PS51189"
FT DOMAIN 3375..3699
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT DOMAIN 3697..3729
FT /note="FATC"
FT /evidence="ECO:0000259|PROSITE:PS51190"
FT REGION 467..498
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2462..2484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3161..3203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3161..3200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3729 AA; 419579 MW; 6F11450DD7949B45 CRC64;
MSASIDGFIA RLSDTQSDYK TKLNVATDLR DSVELHQVTA DSEQFATRVL PEILRLLKSV
PISMVAQAPE HQLRYCLLDV LSRLQYSDAL RPAAVEILQT VMDIFQVDNE ENGFLCMKIV
TNLHRAYKGL LVDQVQPFLD IVITIFKNIP RMVDELFNNQ PGGQSPLTYA GSPPGSVGVE
TPGEGANSST PMFKATASFK VLTECPIIIV LLYSTHKQIA STSLPEFVPY IIDILSIEAK
PQAKEHEAAA LKGDIFTGVS PAIKHRAAYN DFIVSQIKVM SFLAYALRAF SGLLQKYYNL
VPNFVVRLLK DCPPELSSAR KELLVSMRHI LATDFRTFFI SKVDVLLEER VLIGSGLTSY
ETLRPLAYST MADLIHHVRN ELSISQIWKT VRVYCRNMHD NSLATSFQVM SAKLLLNFME
RIIGLPDKQE GRQIMTVILK AFVDRFETLN RTYLELVPGT KANIAKMGKK PEKTDGDEVK
KEGDDVDMED ANDSESINPT WTDLMMEMPI KLHAEVPNHD VKDARFIFRN LMTFIKTVMF
GFKSCNPPPP HPTISLQQWQ EAARTCTHDD VTLFRRLFRE GIVGQQFFAL PIASDNERYD
SGPLVPLVSN KDVKDMMEAF ATVYIHIDPA TFNEIISAEL QFLYEAIFDN PALLHIVHLF
LGSETTSANF TAALLEFLIK KMPEMGEGTA KKTNVLMRLF RQCFTALNMF PAVNEQVMLP
HLTEIIVEAL KLTSTAKEPF VYFYLLRALF RSIGGGRFES LYQAVLPLLP VVLETLNKRL
ETTRVAQERD IYVELCLTVP VRLSLLVPHL SYLMRPLVAA LNGSPELVSQ GLRTLELCVD
NLTSNYFDPI IEPVLDEVMQ ALWKHLKPLP YTHQHSHTTL RILGKLGGRN RAFLTAPTDL
ESMSAMSQDT SVLLAFDGLG EELPVRVTPA VTQALKILEN PLMNPHYRQQ AFNMISVVIK
QFIDTTPLPE NAGSIVQACV KAGVYSSFTE APPLPDGSDR NLVARNMANE LTERLLEAVF
FAASVDETRD AAHELIVNLT EHLTVLELGE FTVEKRRAMR SFSLEDHEGI PYIETRTLLT
AIVYALSHFN QHVKDAGLLA LRTIYSSGRT LCGESVSVYR YPLLRAVFAK LIHACFEEPF
YRKAGACLGL KTIIIELGLP LSWLQARQVE IVRTLFFGIK DVSDDAPSKI REEAAELLYH
TIRSCNGPLT DEQISQRPFL PLSSLLAYEV ESPNPAVRET AKKALELLAE VVGHPVTAII
KQVTNVFLNP IFGKPLRALP FPMQIGYIDA VSYCLALPDT FLRFNDKFTR LLEEALALVE
AEDESLTSSH RMPEYNTQQQ LTKLRVVCIK LLSLALTTSD HLATENPQMR AKIIGVFFKM
LCSNSKKAVD AAHTALGAVL AKSPSRLPKD LLQSGLRPIL VNLSDHKRLT LNGLEGLARL
LELLTYYFKV EIGKKLLDHF KAWTESERMI LVSVRPLEGE ERVKIGVAIL NVFHLLPTTA
HIFIPSVIDA LVYIEGSVRR IQTSPFRAPI AKFLNRQAPD AFLYFKTKLT DAQYGRLLCD
FFDMEETRDL QAYTRENIDQ LVEVVLNDQP DDTKCISACN LIFCLHRLPG LDWIKEQSAL
AQQLIGLIGE LMGATARLSP VSQLHFAIGS AIEELQQFII DYARASDDHS IVLSLIGAVY
SAGAEISWCV QDYLYETVII SHDVELRNVV LKEAFELVLR PSSPLTARTY IMNAIVNPVL
TVEIKRKGNL LELFEKAANG NFMDLVSKEV WLALASTGPA STIDKFQLAL LEMSVLIIKS
SSPLVADVRK DAIKFGWSFL RHEDIVSKMS AYVYIATFVS VFDSLPKIVN QIYVVLLKTH
QPEAKSLVTQ ALETLAPVLV ARTNSMWAKW PRRILSEDGH NAAQVSNIYT FMAKNPVLFY
EYRHQFVPFI VAAIAKLSVA PPNASAVTPF DLGLSGLLAD WEVRAIEELK TTDAKVYTVP
TPQREAVVTY LVRYVCALNV RVVTTGAGPE ILESLDRLLG IWPEAEVRLN FLERALVQSD
LSATESLTAC LNALEVVRLA LKHKHTEYIT QNMDQFAGLF AKTLRSPVLE VHETLKPSLE
KVLAAIPASE LEPEELAVQP VFQIVFNALQ EHLGSTVPPP CWVLLAQHAM KLRADSIDSL
LSQIIKAFSK SVKEVLEENA IRTQVPPAAA AAAAAAAAAV PGSSNPAGGA QNVPPAANGA
AAAVAAVPEE KEQPITVALL IEMMDLLASR ISHLSDQRRF FLSLIAQCIE RIPDDSLARH
IIQMVRSWVF SRSEPFPTIK EKAAILQKML AYDSPKDREL AHTYYELIID VFTDDHLRKT
ELPARLEQPF LLGTTGRAST GDVEIRKKLL SIFSDSLEDN VLKRLLYVFQ EQNWEPLADL
QWLNQALALF YGTAAMSHPL RLPETDTFRF APFSILETNL SPLSDGKDNK EDVDMADIPG
EEAEGEASEL GAASKERTNP AEPEFAEVSD DLAEFLTRRT AFMKSASETK VADFILPLAE
LQCQSKELVH QVWLDVFPRL YSAVPSKDRQ DLIQAIATLM AREYNVRQAD LRPNVVQTIL
EAVAQVEHLP PQLVRYLAGN FDAWYAGLQI LESIQALPRT ESAKIAETNL DALTELYAQL
QENDMFYGLW RTRSKFHVTN AALSYEQCGM WNRAMQMHES AQIKARSGVL PYGEAEYGLW
EDHWILCAEK LQHWDILTEL AKHEGFNDLL LECGWRVADW ISDKEPLQQS VKSLMDVPTP
RRQVFETFLC LQGFAQKTDT LQALSKCCDE GIQLALRKWH GLPRRITGAH IPLLHTFQLY
VEFMEASQVY TSLASTTGLN LEVKSQELKG VLQAWHERLP NPWDDINIWG DLVTWRQHVF
NVINKVYQPL SQPPGPTSTT NSAAFRGHHE IAWIINRFAH VARKQNMPEV CINLLTRIYA
LPNIEIQEAF LKLREQAKCH CENLNDETTG LEVISNTNLI YFGAAQKSEF FTLKGMALAK
LGREDNANEA FASAVQIDVY LPKAWAEWGK FNDKRFKDHP EESFYGSTAI SCYLQAAGLY
KNAKARKLLG RILWLISLDD DKGSLAQAFE SYRGEVPVWY WVTYIPQLLT SLAHREAKLT
RRILIKIAKT FPQALHFHLR TVREEYNILQ RQAMAARPNT NQPIGQAVNS PASTPAGSGH
TGANGNQSNT AGSGSTPTAE EPRQPWEYAE EIHSVLKTAY PLMLLSLETL VDQISHRFRS
PADEDAYRLI VALLNDGMQY MARWNCQRDA KLPPATEASI LRFVEGVVPA HIKGAFERDF
VTDKPDLETY VVRLRQWRNR IEAKLDARPD KINLEALSPP LSEFHHQKFE DVEVPGQNLQ
LTDTNLHFVK IGRFLPGVDI VRGYGICYRR FTLRGHDGSL HPFAVQFPAA RHCRREERVT
QLFRILNNVM LRRNEARLRH LQFTLPCAVP LSNHIRLVQD DTRYISMYQI YERFCRARGQ
SRDAPFDYMT EKLRASSDSR LPKPDLVAVK MEILSGIQAS LVPNTVMRDF FVDQYCSFED
FWLFRKQFAY QYAGITFMTF MMSINNRFAH KFQINMGSGN IWATEMLPVL PSSKNLPAFN
NGEPVAFRLT PNIQTLMGPT TLEGLYAMSV MIIAKGLTEP EFSLDQYLPV FVRDELISWY
AQQQRPSVQD SQLRDMVRVN VDAIVKRASS LTQSSQLNIP ANQTIIDLIS AAVNPRNLAI
TDSLWMAYF
//
