ID A0A2T0FLK6_9ASCO Unreviewed; 1382 AA.
AC A0A2T0FLK6;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN ORFNames=B9G98_03498 {ECO:0000313|EMBL:PRT55878.1};
OS Wickerhamiella sorbophila.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Trichomonascaceae; Wickerhamiella.
OX NCBI_TaxID=45607 {ECO:0000313|EMBL:PRT55878.1, ECO:0000313|Proteomes:UP000238350};
RN [1] {ECO:0000313|EMBL:PRT55878.1, ECO:0000313|Proteomes:UP000238350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS02 {ECO:0000313|EMBL:PRT55878.1,
RC ECO:0000313|Proteomes:UP000238350};
RA Ahn J.O.;
RT "Genome sequencing of [Candida] sorbophila.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRT55878.1}.
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DR EMBL; NDIQ01000022; PRT55878.1; -; Genomic_DNA.
DR STRING; 45607.A0A2T0FLK6; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000238350; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000238350}.
FT DOMAIN 546..735
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 246..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1332..1382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1335..1382
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1382 AA; 152023 MW; D5D309C3DF963A79 CRC64;
MQCAVDSGYL VANECIAIMS AMRKSSRQTH SGIAAILGTQ NEDGDTTLSE RLGLRTSNKV
NVSTTSQPLI WAFAKLRSEI ESKNFSDLTA VALVDPFIAV IKAPSTTGAI TSLALSALEK
MVVLKVINTK MPDIGEALYK VAMAITNCRF RATDQYEDDA VLVQLMGVLD KIIVSELGLG
LCNEAVCELV ETCLSMACQM RRGDALRRSV VSTVTGLMRL VFSQLPFEDQ GSRDFGDDVL
NIESPMPQND MSSGNTAGTF AATDSTTAET DSVNGDAASI AASTTDGNPS QQANGTDKKE
IDTAPFSTPA ILETFRVLVS ITNPQSQHAY TDSTRVMVLR ILRVCFEIAG RGIAQHSAFV
TLISAHLFKY LAQLVRREHP ALVYESLQLV GLIMETGGQH YKLQLEFILA YLLGALAPLT
DLPRDTSMDD IFYDGIVVRP ACVKPPGPNA TSRAPEIREI MVETLTRFSH GVSFFPSLFA
NYDCDTSQTD MCQDLVGFLC RSAYPDSATW STPAVPPLCL EAVLALLQRI TSRSSLITEQ
EPQEVTEAIE RKRRKDIEIV VTTEFNKSPK KGIELMLERG VISEQSPQAI AAFLRSSRRL
HKGELGRFLA RAVNKDILRS FIDGFDFTEK RIDEALREFL CCFRLPGESA EIEPIFERFS
EHYIANGCHS DQVANADAAF VLAYAVIMLN TDQHSPQVKR RMEFDSFKNN LRGANNGKDF
NEDYLREIYT TIKHREIVLP EEHDTDETFE YAWRELQLSL PQASEFETNA SPYIDRYVFA
NSWRPIVSTL SFIFATATDD VVFSRVITGF RQAASLAAKF ELQPAFDHIV RCLAKISTLA
SGDLVVPKTN LCVAIYRDDG TTYDVIVSDL SSPFGSDLKA QMASITMFKI FSDAVENKQL
DALSPQGWEL FARVVTNLYI YDLFVPPGLD RVPAAYRFER GKAGRNVGIF SALSSYLTAN
PDEPSEPSDE EVDAALGAQD CVTACNVLTI VDNIIKICAE SSDIAETAID GIMAALPPAG
SKYSASRIML LELSLKMAGG RSEHAEKIAS VCANAEGNFD GLVPLHAALV SGKLDLVDQM
LANLETADGL LSMPNLPVGS ARLWQLLETS DLSLAAAFAK EHSAEVTPEA RPAAEHALAV
LASKGSEDAL DALYGMQNLN RSPEEVASYL TALQEPCYMA LTKELREGAV ARLQKILLEQ
QTAKSGESWQ RIFDVAVIGL LNQLLKPEVF NCDATGMERT RQQASSLGGK VFLHYAMRSD
VDIEKPWLAL LRVLDRLLSS RRQPALQESV TEMLKNVVLV MRMAGHGTEE FWNDSERQLK
GFVPEIAALV RKNLEPEPVP EREPELSTEK TPETPESKVE DATANETEEV PSEQAETRKN
EE
//
