ID   A0A2T0LQM5_9ACTN        Unreviewed;       925 AA.
AC   A0A2T0LQM5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=DNA-binding SARP family transcriptional activator {ECO:0000313|EMBL:PRX45719.1};
GN   ORFNames=B0I32_1476 {ECO:0000313|EMBL:PRX45719.1};
OS   Nonomuraea fuscirosea.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Nonomuraea.
OX   NCBI_TaxID=1291556 {ECO:0000313|EMBL:PRX45719.1, ECO:0000313|Proteomes:UP000238312};
RN   [1] {ECO:0000313|EMBL:PRX45719.1, ECO:0000313|Proteomes:UP000238312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.7104 {ECO:0000313|EMBL:PRX45719.1,
RC   ECO:0000313|Proteomes:UP000238312};
RA   Whitman W.;
RT   "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT   soil and plant-associated and newly described type strains.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PRX45719.1}.
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DR   EMBL; PVNG01000047; PRX45719.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2T0LQM5; -.
DR   Proteomes; UP000238312; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd15831; BTAD; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR   PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00028; TPR; 4.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:PRX45719.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000238312}.
FT   DOMAIN          17..89
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|SMART:SM00862"
FT   DOMAIN          96..240
FT                   /note="Bacterial transcriptional activator"
FT                   /evidence="ECO:0000259|SMART:SM01043"
SQ   SEQUENCE   925 AA;  100077 MW;  A239012063ADD90F CRC64;
     MTMEIGYLGP WQVTLGGRRV GLVGRRRVAV LTRLALDAGR PVTMQQLVTD VWGQSSTATA
     GKQLHIVVSK LRDALTPDTI ATVPGGYLLD LPRDRVDAHL FTRLAGQARA ARHQREPGTA
     DALFRRALAL WRGSALAEMA DPWARIEAKR LEEERMAAFE DHIELRLARG EQHGVVADLT
     PYVLAHPLRE GPRAQLMLAL YRADRASEAL AVYREGHVAM VEELGLEPGA RLRRLRQAVL
     DGDPALELGT PEQSATIVPA ELPAGIQSFT ARQEEAEWLR EALLSTGVAV VDGPGGVGKS
     ALAVHVAHTM AGRFGDGVVY VDLNGATPGV QPLSVLDALG HLLRSLGLDG TAVPADLDGA
     TARYRSLTKA SDLLVILDNA LDAGQVRPLI PAGADCRALI TSRAALSTLD RARHLHLSGL
     GDRDAVTLLA RIAGQEPVER EPEAAARIAE LCGGFPLAIR IAGARLAARP GRRLADLADR
     LADATHRLDT LQYADLAVRA GIAVSHQHLR EESGGGHDAA HVLPLLGLLD TPTHTPAATA
     ALAGWPEARA EAALERLHDA RLLEAAGPGR YRFHDLIRLY AREQAGELPG QDGAAALRRG
     LHHYLASANT ATQRVHSQVQ EPYYAAEQPG VAFTGAQEVR EWTEAERDNL LAVAHQAAES
     ADPDTAIGLA LSLHWPFNYR GWVTHLTDVH LNAIAVAARC GDWAGQAQAA TFLGWVYRDQ
     GRHEQAVEQL KEAVVYWGKA GLPHRRIGAF NNLGIIHTLQ GQLDLARINF ARATEIAEKT
     GDVYARSAIH NNGVHLLYRQ GRFEEAIAQA KTAVVEWTGS LYVEGASHET LARAYLHAGR
     LVEAADTFQV ALTLLREAGY RIGHAVAAWW CGHTLHELGR PAEARRVWRD CFTSLLEARL
     LTRAEVDDLL DQPVPEMPGP IGNML
//