ID A0A2T0M1B4_9PSEU Unreviewed; 823 AA.
AC A0A2T0M1B4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=B0I33_102499 {ECO:0000313|EMBL:PRX50378.1};
OS Prauserella shujinwangii.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Prauserella.
OX NCBI_TaxID=1453103 {ECO:0000313|EMBL:PRX50378.1, ECO:0000313|Proteomes:UP000238362};
RN [1] {ECO:0000313|EMBL:PRX50378.1, ECO:0000313|Proteomes:UP000238362}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7125 {ECO:0000313|EMBL:PRX50378.1,
RC ECO:0000313|Proteomes:UP000238362};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRX50378.1}.
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DR EMBL; PVNH01000002; PRX50378.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0M1B4; -.
DR Proteomes; UP000238362; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17574; REC_OmpR; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005561; ANTAR.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF03861; ANTAR; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01012; ANTAR; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50921; ANTAR; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000238362}.
FT DOMAIN 119..174
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 353..572
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 619..735
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 745..806
FT /note="ANTAR"
FT /evidence="ECO:0000259|PROSITE:PS50921"
FT REGION 597..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 668
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 823 AA; 88597 MW; C8FBBEFAF696EB02 CRC64;
MTALNSGDTA WKAETLFAGP GDTLARLRAF DWASSPLGPV ERWPAELRAA VRTVLPSRVP
MLLWWGPQLT QIFNEAFTPL LGEKYPDAIG QPAAECWAEV WPEVGPLAEQ VLRGDGATYS
ENLRLFMRRH GYLEETYWTF SYSPIHDERG EVAGVFVATT DMTPRVVGDR RLDTLRRLGS
LSLAGPTTGG GAAAACTEAI RVLGDNRADL PLVAAYLWGE GDESDGLRLV ASAGITEGGG
LGGDGLRSVL RRVARGGAAE HVTDLANRLP GSAEVDEALV LPLRPGGQER PAGALLLGLS
PYRELDGSYR GFAELVTDRV STVLADAGVL ASEGRRVAAL AELDAAKTRF FQNVSHEFRT
PLTLLLSPLR ELLDEHAGVL PAAQRESMEA AYRAAQRLRR LVDTLLDVAR AESAQLRPRP
SPTDVAALTA DCAAMFHSVA EEAGLELRVH VPATAGGLAL LDQDMWARIV FNLLSNAVKF
TPAGSVTLTL RVEGDRIVLS VADTGTGIAR EQQERIFDRF HQVPEVRSRS REGSGIGLSL
VADLVGALGG EVGVDSEPGR GSTFTVTVPL VPAHGPDGGD PSGRATVEDV APGFVSESRQ
WEPAAGEDGA GSPARPDRTI LLVEDNADMR RYLVRLLREQ HWAVEVAADA ETALARAETA
SPDLVLSDVM LPGDDGIALL KDIRSHPRLA RVPVVLLTAR AGPESAAEGL RHGADDYVVK
PFEPGELVGR VRVHLELSAF REELLAAKES EADNLRTALD TRTVISQAIG LVMASRACPA
EEAFRHLREL SQERNVKVRQ VAQEIIDDFL DELASADLER RER
//
