ID A0A2T0M339_9PSEU Unreviewed; 664 AA.
AC A0A2T0M339;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Cell division protein FtsI (Penicillin-binding protein 3) {ECO:0000313|EMBL:PRX51140.1};
GN ORFNames=B0I33_101293 {ECO:0000313|EMBL:PRX51140.1};
OS Prauserella shujinwangii.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Prauserella.
OX NCBI_TaxID=1453103 {ECO:0000313|EMBL:PRX51140.1, ECO:0000313|Proteomes:UP000238362};
RN [1] {ECO:0000313|EMBL:PRX51140.1, ECO:0000313|Proteomes:UP000238362}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7125 {ECO:0000313|EMBL:PRX51140.1,
RC ECO:0000313|Proteomes:UP000238362};
RA Whitman W.;
RT "Genomic Encyclopedia of Type Strains, Phase III (KMG-III): the genomes of
RT soil and plant-associated and newly described type strains.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PRX51140.1}.
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DR EMBL; PVNH01000001; PRX51140.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2T0M339; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000238362; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:PRX51140.1};
KW Cell division {ECO:0000313|EMBL:PRX51140.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000238362};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 112..285
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 331..639
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 25..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 664 AA; 70966 MW; 3CBD020B89B9B39A CRC64;
MAGKARPRGG IRAGGGARAR AAGAAAAGTR GGARAGGKAR AAGGARRTYS ARARRGGVSA
ADHGHRNRFK AGRILLVVLL VAAGLKLVHI QTFEAEALSA KAERQRTTTI DIPAQRGSIV
DRNGAKLAFS VETRTLWANL RLMRKNWAEY AREHPGTDLN YDRRVEQIAT YIAGRLPART
SEQELLDLFH KDASFTYLVD GVEPSVADDI TEKFPEIGFE KRAEREYPGG ELASNILGLA
NWRMESPDVS KHNIHGLAGL ELTRDDDLAG QPGRQIVDTA QGNDVVIPGT ERDLRPAVPG
SDLELTIDSD AQYVLQNELS SYVAESKAQG GSAVILDSQT GEVYALADSK PFDPNDTSDL
DPEALRNDAI SLPFEPGSVN KVVTAAAAIE AGVAKPDSVF EVPDSIEVAD HVVHDAWQHP
TQKFTTTGIF AKSSNVGTLM LAEKLGPERF VRMLEKFGLG QRTGIGLPGE SPGYVPPRED
WSGTTFGNLP IGQGLSMTVV QMASMYQAIA NDGVRVEPRV VKAKITPDGA RVPEPAPQET
RVVSERTADT VKNMLRAVTQ DGEGFDRGTG TAAALEGYQI SGKTGTGQQV DPDTGAYSDH
LYNITFAGIL PADNPRFVVG IRLDAPQASS SAAPLFHDIA SYLAQRYQIP LSDQPTPVVP
LVLS
//
